Western Blot (WB)
(Western blot analysis of CIDE-B in mouse small intestine tissue lysate with CIDE-B antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Rabbit CIDE-B Polyclonal Antibody | anti-CIDE-B antibody
CIDE-B Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
CIDE-B; Polyclonal Antibody; CIDE-B Antibody; Cell death-inducing DFF-like effector B; anti-CIDE-B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
CIDE-B antibody has no cross activity to CIDE-A.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
219
Applicable Applications for anti-CIDE-B antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B.
Target Name
CIDE-B
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of CIDE-B in mouse small intestine tissue lysate with CIDE-B antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of CIDE-B in mouse small intestine tissue lysate with CIDE-B antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CIDE-B in human small intestine tissue with CIDE-B antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of CIDE-B in human small intestine tissue with CIDE-B antibody at 5 ug/mL.)
Related Product Information for anti-CIDE-B antibody
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow.
Product Categories/Family for anti-CIDE-B antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
24,678 Da
NCBI Official Full Name
Cide-b
UniProt Protein Name
Cell death activator CIDE-B
UniProt Gene Name
CIDEB
UniProt Entry Name
CIDEB_HUMAN
Uniprot Description
CIDEB: Activates apoptosis.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 14q12
Cellular Component: cytosol; lipid particle; perinuclear region of cytoplasm
Molecular Function: identical protein binding; protein binding
Biological Process: apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis
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Product Notes
The CIDE-B cideb (Catalog #AAA9401433) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CIDE-B Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CIDE-B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CIDE-B cideb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIDE-B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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