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Immunohistochemistry (IHC) (Anti-CHD7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Goat CHD7 Polyclonal Antibody | anti-CHD7 antibody

Goat Polyclonal to Human CHD7

Gene Names
CHD7; CRG; HH5; IS3; KAL5
Reactivity
Human
Predicted Reactivity: Gorilla, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
CHD7; Polyclonal Antibody; Goat Polyclonal to Human CHD7; Anti-CHD7 Antibody (Internal) IHC-plus; ATP-dependent helicase CHD7; HH5; KAL5; CHD-7; IS3; KIAA1416; Human CHD7; anti-CHD7 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Predicted Reactivity: Gorilla, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human CHD7.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
2997
Applicable Applications for anti-CHD7 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA (1:64000), IHC-P (3.75 ug/ml)
Target Species
Human
Immunogen Description
Synthetic peptide C-KDEIDEFANSPSE from an internal region of human CHD7 (NP_060250.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Gibbon (92%), Monkey (92%), Marmoset (92%), Mouse (92%), Rat (92%).
Immunogen Type
Synthetic peptide
Immunogen
CHD7 antibody was raised against synthetic peptide C-KDEIDEFANSPSE from an internal region of human CHD7 (NP_060250.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Gibbon (92%), Monkey (92%), Marmoset (92%), Mouse (92%), Rat (92%), Elephant (92%), Panda (92%), Bovine (92%), Dog (92%), Bat (92%), Horse (92%), Pig (92%), Opossum (92%), Turkey (92%), Chicken (92%), Lizard (92%), Rabbit (85%).
Antigen Modification
Internal
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-CHD7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC) (Anti-CHD7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
101,085 Da
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 7
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 7
NCBI Official Symbol
CHD7
NCBI Official Synonym Symbols
CRG; HH5; IS3; KAL5
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 7; CHARGE association; ATP-dependent helicase CHD7; chromodomain helicase DNA binding protein 7 isoform CRA_e
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 7
UniProt Gene Name
CHD7
UniProt Synonym Gene Names
KIAA1416; CHD-7
UniProt Entry Name
CHD7_HUMAN

NCBI Description

This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

CHD-7: Probable transcription regulator. May interact with CTCF. Interacts with CHD8. Widely expressed in fetal and adult tissues. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus; Helicase; DNA-binding; EC 3.6.4.12

Chromosomal Location of Human Ortholog: 8q12.2

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; chromatin binding; helicase activity; ATP binding

Biological Process: heart morphogenesis; limb development; central nervous system development; olfactory behavior; blood circulation; palate development; positive regulation of multicellular organism growth; regulation of growth hormone secretion; adult walking behavior; female genitalia development; embryonic hindlimb morphogenesis; olfactory nerve development; sensory perception of sound; regulation of neurogenesis; regulation of transcription, DNA-dependent; skeletal development; T cell differentiation; adult heart development; inner ear morphogenesis; transcription, DNA-dependent; in utero embryonic development; olfactory bulb development; semicircular canal morphogenesis; cranial nerve development; chromatin modification; genitalia development; retina development in camera-type eye; artery morphogenesis; cognition; nose development; rRNA processing

Disease: Charge Syndrome; Tracheoesophageal Fistula With Or Without Esophageal Atresia; Hypogonadotropic Hypogonadism 5 With Or Without Anosmia

Research Articles on CHD7

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Product Notes

The CHD7 chd7 (Catalog #AAA246843) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human CHD7 reacts with Human Predicted Reactivity: Gorilla, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's CHD7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA (1:64000), IHC-P (3.75 ug/ml). Researchers should empirically determine the suitability of the CHD7 chd7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHD7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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