Rabbit CEP41 Polyclonal Antibody | anti-CEP41 antibody

CEP41 Polyclonal Antibody

Cat. Num. AAA3007083

• Gene Names: CEP41; JBTS15; TSGA14
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: CEP41; Polyclonal Antibody; CEP41 Polyclonal Antibody; Centrosomal protein of 41 kDa; Cep41; Testis-specific gene A14 protein; TSGA14; anti-CEP41 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: CEP41 polyclonal antibody detects endogenous levels of CEP41 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 373

• Applicable Applications for anti-CEP41 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human CEP41.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of CEP41 polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysateLane2:Raw264. 7 whole cell lysateLane3:PC12 whole cell lysate)

Related Product Information for anti-CEP41 antibody

Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP41 (centrosomal protein of 41 kDa) gene encodes a protein of 373 amino acids that is alternatively spliced into 4 isoforms. Isoforms 1 and 4 are expressed in testis, as well as in and fetal brain and liver.

NCBI and Uniprot Product Information

• NCBI GI #: 16306479
• NCBI GeneID: 95681
• NCBI Accession #: NP_061188.1
• NCBI GenBank Nucleotide #: NP_061188.1
• UniProt Accession #: Q9BYV8
• Molecular Weight: ~ 15kDa
• NCBI Official Full Name: centrosomal protein of 41 kDa isoform 1
• NCBI Official Synonym Full Names: centrosomal protein 41
• NCBI Official Symbol: CEP41
• NCBI Official Synonym Symbols: JBTS15; TSGA14
• NCBI Protein Information: centrosomal protein of 41 kDa
• UniProt Protein Name: Centrosomal protein of 41 kDa
• Protein Family: Centrosomal protein
• UniProt Gene Name: TSGA14
• UniProt Synonym Gene Names: CEP41
• UniProt Entry Name: CEP41_HUMAN

NCBI Description

This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]