Rabbit TUBB1 Polyclonal Antibody | anti-TUBB1 antibody

TUBB1 Polyclonal Antibody

Cat. Num. AAA3006948

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: TUBB1; Polyclonal Antibody; TUBB1 Polyclonal Antibody; Tubulin beta-1 chain; anti-TUBB1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TUBB1 polyclonal antibody detects endogenous levels of TUBB1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 451

• Applicable Applications for anti-TUBB1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human TUBB1
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of TUBB1 polyclonal antibody at 1:500 dilutionLane1:HEK293Twhole cell lysateLane2:Raw264. 7 whole cell lysate Lane3:PC12 whole cell lysate)

Related Product Information for anti-TUBB1 antibody

Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and e Tubulin are associated with the centrosome. d Tubulin is a homolog of the Chlamydomonas d Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.

NCBI and Uniprot Product Information

• NCBI GI #: 13562114
• NCBI GeneID: 81027
• NCBI Accession #: NP_110400
• NCBI GenBank Nucleotide #: NP_110400.1
• UniProt Accession #: Q9H4B7; Q13885; Q9BVA1; P68371; Q13509; Q99867; P04350; P07437; Q9BUF5; Q3ZCM7
• Molecular Weight: ~ 50kDa
• NCBI Official Full Name: tubulin beta-1 chain
• NCBI Official Synonym Full Names: tubulin beta 1 class VI
• NCBI Official Symbol: TUBB1
• NCBI Protein Information: tubulin beta-1 chain
• UniProt Protein Name: Tubulin beta-1 chain
• Protein Family: Tubulin
• UniProt Gene Name: TUBB1
• UniProt Entry Name: TBB1_HUMAN

NCBI Description

This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]