Western Blot (WB)
(Western Blot (WB) analysis of CEP76 (L284) polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate (40ug) Lane2:MCF-7 cell lysate (40ug) Lane3:The Spleen tissue lysate of Rat (40ug))
Rabbit anti-Human, Rat CEP76 Polyclonal Antibody | anti-CEP76 antibody
CEP76 (L284) Polyclonal Antibody
Gene Names
CEP76; C18orf9; HsT1705
Reactivity
Human, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CEP76; Polyclonal Antibody; CEP76 (L284) Polyclonal Antibody; Centrosomal protein of 76 kDa; Cep76; centrosomal protein 76; C18orf9; anti-CEP76 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CEP76 (L284) polyclonal antibody endogenous levels of GPR87 protein.
Purity/Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
584
Applicable Applications for anti-CEP76 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 224-344 of Human CEP76
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -22 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -22 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of CEP76 (L284) polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate (40ug) Lane2:MCF-7 cell lysate (40ug) Lane3:The Spleen tissue lysate of Rat (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of CEP76 (L284) polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate (40ug) Lane2:MCF-7 cell lysate (40ug) Lane3:The Spleen tissue lysate of Rat (40ug))
Related Product Information for anti-CEP76 antibody
Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP76 (centrosomal protein of 76 kDa) gene encodes a protein of 659 amino acids. The CEP76 protein is homologous among several species including human, mouse, rat and xenopus, suggesting a conserved function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 74kDa
NCBI Official Full Name
centrosomal protein of 76 kDa isoform b
NCBI Official Synonym Full Names
centrosomal protein 76
NCBI Official Symbol
CEP76
NCBI Official Synonym Symbols
C18orf9; HsT1705
NCBI Protein Information
centrosomal protein of 76 kDa
UniProt Protein Name
Centrosomal protein of 76 kDa
Protein Family
UniProt Gene Name
CEP76
UniProt Synonym Gene Names
C18orf9; Cep76
UniProt Entry Name
CEP76_HUMAN
NCBI Description
This gene encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Uniprot Description
CEP76: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication. Belongs to the CEP76 family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 18p11.21
Cellular Component: centriole; centrosome; protein complex; cytosol
Molecular Function: protein binding
Biological Process: regulation of centriole replication; organelle organization and biogenesis; mitotic cell cycle; G2/M transition of mitotic cell cycle
Research Articles on CEP76
Similar Products
Product Notes
The CEP76 cep76 (Catalog #AAA3013914) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CEP76 (L284) Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CEP76 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the CEP76 cep76 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEP76, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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