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Western Blot (WB) (Western blot analysis of CEA(CD66e) expression in Human colon cancer lysate.)

Rabbit anti-Human CEA Polyclonal Antibody | anti-CEA antibody

Anti-CEA (CD66e) Rabbit pAb

Gene Names
CEACAM5; CEA; CD66e
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Purity
Affinity Chromatography
Synonyms
CEA; Polyclonal Antibody; Anti-CEA (CD66e) Rabbit pAb; adhesion molecule 5; CD66e; Ceacam5; Meconium antigen 100; anti-CEA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
CEA(CD66e) Antibody detects endogenous levels of total CEA(CD66e)
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
702
Applicable Applications for anti-CEA antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Immunogen
A synthesized peptide derived from human CEA(CD66e)
Subcellular Location
Cell membrane; Lipid-anchor; GPI-anchor
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of CEA(CD66e) expression in Human colon cancer lysate.)

Western Blot (WB) (Western blot analysis of CEA(CD66e) expression in Human colon cancer lysate.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using CEA(CD66e) Antibody.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using CEA(CD66e) Antibody.)

Immunofluorescence (IF)

(Immunofluorescent analysis of MCF-7 cells, using CEA(CD66e) Antibody.)

Immunofluorescence (IF) (Immunofluorescent analysis of MCF-7 cells, using CEA(CD66e) Antibody.)
Related Product Information for anti-CEA antibody
Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
180-220kDa
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 5 isoform 1 preproprotein
NCBI Official Synonym Full Names
carcinoembryonic antigen related cell adhesion molecule 5
NCBI Official Symbol
CEACAM5
NCBI Official Synonym Symbols
CEA; CD66e
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 5
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 5
Protein Family
UniProt Gene Name
CEACAM5
UniProt Synonym Gene Names
CEA; CEA

NCBI Description

This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

Uniprot Description

Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.

Research Articles on CEA

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Product Notes

The CEA ceacam5 (Catalog #AAA4750745) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CEA (CD66e) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CEA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200. Researchers should empirically determine the suitability of the CEA ceacam5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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