Streptozotocin (Zanosar), Inhibitor

Streptozotocin (Zanosar)

Cat. Num. AAA386226

• Purity: >98%
• Synonyms: Streptozotocin (Zanosar); Streptozocin; Zanosar; STZ; inhibitor

• Purity/Purification: >98%
• Form/Format: Powder
• Concentration: 0.1 mM: 37.71 mL (1 mg); 188.54 mL (5 mg); 377.07mL (10 mg); 0.5 mM: 7.54 mL (1 mg); 37.71 mL (5 mg); 75.41 mL (10 mg); 1 mM: 3.77 mL (1 mg); 18.85 mL (5 mg); 37.71 mL (10 mg); 5 mM: 0.75 mL (1 mg); 3.77 mL (5 mg); 7.54 mL (10 mg) (varies by lot)

• CAS Number: 18883-66-4
• Formula: C8H15N3O7
• SMILES: CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
• Actions: Inhibitor
• In Vivo Solvent: Saline
• Solubility (DMSO): 53 mg/mL (199.83 mM)
• Solubility (Ethanol): <1 mg/mL (<1 mM)
• Solubility (in vivo): 30 mg/mL
• Solubility (Water): 53 mg/mL (199.83 mM)
• Availability: We cannot ship this item to Switzerland, Italy, Germany, France and Austria.
• Preparation and Storage: at -20 degree C 3 years Powder

Chemical Structure

Related Product Information for Streptozotocin (Zanosar), inhibitor

Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.

References

D.H. Mhya, .et al. Evaluation of Anti-hyperglycemic Effect of Sub-fractions Derived from Ethanol-aqueous Fraction of Balanites aegyptiaca Leaves in Streptozotocin-induced Diabetic Rats, Asian J Exp Biol Sci, 2019, 12 (2): 164-172
Stanley I. R. Okoduwa, .et al. Validation of the antidiabetic effects of Vernonia amygdalina delile leaf fractions in fortified diet-fed streptozotocin-treated rat model of type-2 diabetes, J Diabetol, 2017, 8(3): 74-85
Stanley I. R. Okoduwa, .et al. Anti-Diabetic Potential of Ocimum gratissimum Leaf Fractions in Fortified Diet-Fed Streptozotocin Treated Rat Model of Type-2 Diabetes, Medicines (Basel), 2017, Dec; 4(4): 73 PMID: 29019956
Stanley I. R. Okoduwa, .et al. Appropriate Insulin Level in Selecting Fortified Diet-Fed, Streptozotocin-Treated Rat Model of Type 2 Diabetes for Anti-Diabetic Studies, PLoS One, 2017, 12(1): e0170971 PMID: 28129400
Stanley I. R. Okoduwa, .et al. Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants, World J Diabetes, 2016, Dec 15; 7(20): 605-614 PMID: 28031778