Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CDKL1 Polyclonal Antibody at dilution of 1:25(×200))
Rabbit anti-Human CDKL1 Polyclonal Antibody | anti-CDKL1 antibody
CDKL1 Polyclonal Antibody
Gene Names
CDKL1; P42; KKIALRE
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
CDKL1; Polyclonal Antibody; CDKL1 Polyclonal Antibody; CDC 2 related kinase 1; CDC 2 related kinase; CDC2 related kinase 1; CDC2 related kinase; CDK L1; CDKL 1; Cdkl1; Cyclin dependent kinase like 1; Cyclin-dependent kinase-like 1 (CDC2-related kinase); Cyclin-dependent kinase-like 1; EC 2.7.11.22; KKIALRE; P42; Protein kinase p42 KKIALRE; Serine/threonine protein kinase KKIALRE; Serine/threonine-protein kinase KKIALRE; anti-CDKL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.6mg/mL (varies by lot)
Sequence Length
358
Applicable Applications for anti-CDKL1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:25-1:100
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Synthetic peptide of human CDKL1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CDKL1 Polyclonal Antibody at dilution of 1:25(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CDKL1 Polyclonal Antibody at dilution of 1:25(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CDKL1 Polyclonal Antibody at dilution of 1:25(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CDKL1 Polyclonal Antibody at dilution of 1:25(×200))
Related Product Information for anti-CDKL1 antibody
The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
Product Categories/Family for anti-CDKL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
cyclin-dependent kinase-like 1 isoform 1
NCBI Official Synonym Full Names
cyclin dependent kinase like 1
NCBI Official Symbol
CDKL1
NCBI Official Synonym Symbols
P42; KKIALRE
NCBI Protein Information
cyclin-dependent kinase-like 1
UniProt Protein Name
Cyclin-dependent kinase-like 1
Protein Family
UniProt Gene Name
CDKL1
UniProt Entry Name
CDKL1_HUMAN
NCBI Description
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. [provided by RefSeq, Nov 2018]
Uniprot Description
CDKL1: a protein kinase of the CDKL family. Accumulates primarily in the nucleus.
Protein type: Kinase, protein; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; Cell cycle regulation; CMGC group; CDKL family
Chromosomal Location of Human Ortholog: 14q21.3
Cellular Component: cytoplasm; nucleus
Molecular Function: cyclin-dependent protein kinase activity; ATP binding
Biological Process: regulation of cell cycle; heart development; protein amino acid phosphorylation
Research Articles on CDKL1
Similar Products
Product Notes
The CDKL1 cdkl1 (Catalog #AAA2561572) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDKL1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDKL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:25-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the CDKL1 cdkl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDKL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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