Rabbit anti-Human CDH26 Polyclonal Antibody | anti-CDH26 antibody

CDH26, CT (CDH26, Cadherin-like protein 26, Cadherin-like protein VR20) (PE)

Cat. Num. AAA6284170

• Gene Names: CDH26; VR20
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CDH26; Polyclonal Antibody; CT (CDH26; Cadherin-like protein 26; Cadherin-like protein VR20) (PE); Cadherin-like protein VR20; anti-CDH26 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-CDH26 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CDH26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 818-846 amino acids from the C-terminal region of human CDH26.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(CDH26 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CDH26 antibody detected the CDH26 protein (arrow).)

Related Product Information for anti-CDH26 antibody

Cadherins are a family of adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization and migration. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This gene encodes a cadherin domain-containing protein whose specific function has not yet been determined. Alternative splicing occurs at this locus and two transcript variants, encoding distinct proteins, have been identified.

Product Categories/Family for anti-CDH26 antibody

Antibodies; Cadherin

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Ferreira, M.A., et al. Allergy 64(11):1623-1628(2009). Deloukas, P., et al. Nature 414(6866):865-871(2001). Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 21361902
• NCBI GeneID: 60437
• NCBI Accession #: NP_068582.2
• NCBI GenBank Nucleotide #: NM_021810.4
• UniProt Accession #: Q8IXH8; Q6P5Y6; Q8TCH3; Q9BQN4; Q9NRU1; A2A2M5; B3KNX3
• Molecular Weight: 13,320 Da
• NCBI Official Full Name: cadherin-like protein 26 isoform b
• NCBI Official Synonym Full Names: cadherin 26
• NCBI Official Symbol: CDH26
• NCBI Official Synonym Symbols: VR20
• NCBI Protein Information: cadherin-like protein 26
• UniProt Protein Name: Cadherin-like protein 26
• Protein Family: Cadherin-like protein
• UniProt Gene Name: CDH26

NCBI Description

This gene encodes a member of the cadherin protein family. Cadherins are a family of calcium-dependent adhesion molecules that mediate cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization, migration and differentiation. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This protein is expressed in gastrointestinal epithelial cells and may be upregulated during allergic inflammation. This protein interacts with alpha integrins and may also be involved in leukocyte migration and adhesion. [provided by RefSeq, Jan 2017]

Uniprot Description

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.