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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human tonsil using CD192 Polyclonal Antibody at dilution of 1:300.)

Rabbit CD192 Polyclonal Antibody | anti-CD192 antibody

CD192 Polyclonal Antibody

Gene Names
CCR2; CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Affinity Purification
Synonyms
CD192; Polyclonal Antibody; CD192 Polyclonal Antibody; C C chemokine receptor type 2; C C CKR 2; C-C chemokine receptor type 2; C-C CKR-2; CC chemokine receptor type 2; CC CKR 2; CC-CKR-2; CCCKR2; CCR 2; CCR-2; CCR1L; CCR2; CCR2A; CCR2B; CCR5L; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Motif Receptor 2; CKR 2; CKR2; CKR2A; CKR2B; CMKBR2; MCP 1 R; MCP-1-R; MCP1 RECEPTOR; MCP1R; Monocyte chemoattractant protein 1 receptor; Monocyte Chemotactic Protein 1 Receptor; anti-CD192 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
1.35 mg/mL (varies by lot)
Sequence Length
360
Applicable Applications for anti-CD192 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:800-1:3000
Immunogen
KLH conjugated synthetic peptide corresponding to Mouse CCR2
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human tonsil using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human tonsil using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded Mouse spleen using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded Mouse spleen using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD192 Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD192 Polyclonal Antibody at dilution of 1:300.)
Related Product Information for anti-CD192 antibody
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Product Categories/Family for anti-CD192 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,064 Da
NCBI Official Full Name
C-C chemokine receptor type 2 isoform A
NCBI Official Synonym Full Names
C-C motif chemokine receptor 2
NCBI Official Symbol
CCR2
NCBI Official Synonym Symbols
CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
NCBI Protein Information
C-C chemokine receptor type 2
UniProt Protein Name
C-C chemokine receptor type 2
UniProt Gene Name
CCR2
UniProt Synonym Gene Names
CMKBR2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; MCP-1-R

NCBI Description

The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]

Uniprot Description

Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels (). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).

Research Articles on CD192

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Product Notes

The CD192 ccr2 (Catalog #AAA2556213) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD192 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD192 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:800-1:3000. Researchers should empirically determine the suitability of the CD192 ccr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD192, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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