Rabbit anti-Human CCDC103 Polyclonal Antibody | anti-CCDC103 antibody

CCDC103 Antibody

Cat. Num. AAA7004458

• Gene Names: CCDC103; SMH; PR46b; CILD17
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: >95%,Protein G purified
• Synonyms: CCDC103; Polyclonal Antibody; CCDC103 Antibody; Coiled-coil domain-containing protein 103; anti-CCDC103 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 242

• Applicable Applications for anti-CCDC103 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Recombinant human Coiled-coil domain-containing protein 103 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western BlotAll lanes: CCDC103 antibody at 5 ug/ml+ Mouse heart tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 28,12 kDaObserved band size: 111 kDa)

Related Product Information for anti-CCDC103 antibody

Dynein-attachment factor required for cilia motility.

NCBI and Uniprot Product Information

• NCBI GI #: 385719202
• NCBI GeneID: 388389
• NCBI Accession #: NP_001245324.1
• NCBI GenBank Nucleotide #: NM_001258395.1
• UniProt Accession #: Q8IW40; A8K145; B8ZZU0
• Molecular Weight: 11,276 Da
• NCBI Official Full Name: coiled-coil domain-containing protein 103 isoform 1
• NCBI Official Synonym Full Names: coiled-coil domain containing 103
• NCBI Official Symbol: CCDC103
• NCBI Official Synonym Symbols: SMH; PR46b; CILD17
• NCBI Protein Information: coiled-coil domain-containing protein 103
• UniProt Protein Name: Coiled-coil domain-containing protein 103
• Protein Family: Coiled-coil domain-containing protein
• UniProt Gene Name: CCDC103
• UniProt Entry Name: CC103_HUMAN

NCBI Description

This gene encodes a protein that contains a coiled-coil domain. [provided by RefSeq, Apr 2012]

Uniprot Description

CCDC103: Dynein-attachment factor required for cilia motility. Defects in CCDC103 are the cause of primary ciliary dyskinesia type 17 (CILD17). A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the CCDC103/PR46b family.

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: axoneme; cytoplasm

Molecular Function: protein binding; protein homodimerization activity

Biological Process: heart looping

Disease: Ciliary Dyskinesia, Primary, 17