Western Blot (WB)
(Western blot analysis of lysates from Hela cell line, mouse brain, mouse testis, mouse lung, mouse spleen, rat brain tissue (from left to right), using Mouse Cbx7 Antibody (C-term). MBS9212668 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit Cbx7 Polyclonal Antibody | anti-Cbx7 antibody
Mouse Cbx7 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from Hela cell line, mouse brain, mouse testis, mouse lung, mouse spleen, rat brain tissue (from left to right), using Mouse Cbx7 Antibody (C-term). MBS9212668 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from Hela cell line, mouse brain, mouse testis, mouse lung, mouse spleen, rat brain tissue (from left to right), using Mouse Cbx7 Antibody (C-term). MBS9212668 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Bernstein E.,et al.Mol. Cell. Biol. 26:2560-2569(2006).
Yap K.L.,et al.Mol. Cell 38:662-674(2010).
NCBI and Uniprot Product Information
Uniprot Description
CBX7: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Protein type: Transcription regulation
Cellular Component: nucleoplasm; heterochromatin; cytoplasm; nuclear chromatin; PcG protein complex; nucleus
Molecular Function: single-stranded RNA binding; RNA binding; chromatin binding; methylated histone residue binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; sebaceous gland development; chromatin modification; negative regulation of transcription from RNA polymerase II promoter
Research Articles on Cbx7
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Product Notes
The Cbx7 cbx7 (Catalog #AAA9212668) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mouse Cbx7 Antibody (C-term) reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cbx7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Cbx7 cbx7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cbx7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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