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Western Blot (WB) (Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 ug/mL.)

Rabbit anti-Human Cathelicidin Polyclonal Antibody | anti-CAMP antibody

Cathelicidin Antibody

Gene Names
CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
Cathelicidin; Polyclonal Antibody; Cathelicidin Antibody; Cathelicidin antimicrobial peptide; Cationic antimicrobial protein; CAP18; FALL39; hCAP-18; HSD26; LL37; anti-CAMP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
173
Applicable Applications for anti-CAMP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the carboxy terminus of the human Cathelicidin.
Target Name
Cathelicidin
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 ug/mL.)

Western Blot (WB) (Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 ug/mL.)
Related Product Information for anti-CAMP antibody
One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
Product Categories/Family for anti-CAMP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
820
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,301 Da
NCBI Official Full Name
cathelicidin antimicrobial peptide preproprotein
NCBI Official Synonym Full Names
cathelicidin antimicrobial peptide
NCBI Official Symbol
CAMP
NCBI Official Synonym Symbols
LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
NCBI Protein Information
cathelicidin antimicrobial peptide
UniProt Protein Name
Cathelicidin antimicrobial peptide
Protein Family
UniProt Gene Name
CAMP
UniProt Synonym Gene Names
CAP18; FALL39; CAP-18; hCAP-18
UniProt Entry Name
CAMP_HUMAN

NCBI Description

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

Uniprot Description

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family.

Protein type: Secreted; Vesicle; Cell cycle regulation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol

Molecular Function: protein binding

Biological Process: interaction with host; defense response to Gram-positive bacterium; positive regulation of angiogenesis; innate immune response in mucosa; killing by host of symbiont cells; defense response to bacterium; positive regulation of cell proliferation; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium

Research Articles on CAMP

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Product Notes

The CAMP camp (Catalog #AAA9411036) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cathelicidin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cathelicidin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CAMP camp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cathelicidin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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