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Western Blot (WB) (Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 μg/mL.)

Rabbit anti-Human Cathelicidin Polyclonal Antibody | anti-CAMP antibody

Cathelicidin Antibody

Gene Names
CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Cathelicidin Antibody is affinity chromatography purified via peptide column.
Synonyms
Cathelicidin; Polyclonal Antibody; Cathelicidin Antibody; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39; Cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; cathelicidin antimicrobial peptide; anti-CAMP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Cathelicidin Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
170
Applicable Applications for anti-CAMP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Cathelicidin.
Buffer
Cathelicidin Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Cathelicidin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 μg/mL.)

Western Blot (WB) (Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 μg/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of Cathelicidin in Human Spleen cells with Cathelicidin antibody at 20 μg/mL.)

Immunofluorescence (IF) (Immunofluorescence of Cathelicidin in Human Spleen cells with Cathelicidin antibody at 20 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of Cathelicidin in human spleen tissue with Cathelicidin antibody at 5 μg/ml.)

Immunohistochemistry (IHC) (Immunohistochemistry of Cathelicidin in human spleen tissue with Cathelicidin antibody at 5 μg/ml.)
Related Product Information for anti-CAMP antibody
Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
820
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 19 kDa

Observed: 18 kDa
NCBI Official Full Name
cathelicidin antimicrobial peptide
NCBI Official Synonym Full Names
cathelicidin antimicrobial peptide
NCBI Official Symbol
CAMP
NCBI Official Synonym Symbols
LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
NCBI Protein Information
cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein
UniProt Protein Name
Cathelicidin antimicrobial peptide
Protein Family
UniProt Gene Name
CAMP
UniProt Synonym Gene Names
CAP18; FALL39; CAP-18; hCAP-18
UniProt Entry Name
CAMP_HUMAN

NCBI Description

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

Uniprot Description

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family.

Protein type: Secreted, signal peptide; Cell cycle regulation; Vesicle; Secreted

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol

Molecular Function: protein binding

Biological Process: interaction with host; positive regulation of angiogenesis; defense response to Gram-positive bacterium; innate immune response in mucosa; killing by host of symbiont cells; defense response to bacterium; positive regulation of cell proliferation; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium

Research Articles on CAMP

Similar Products

Product Notes

The CAMP camp (Catalog #AAA150489) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cathelicidin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cathelicidin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the CAMP camp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cathelicidin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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