Western Blot (WB)
(CARTPT Antibody (N-term) (MBS9201884) western blot analysis in mouse heart tissue lysates(35ug/lane).This demonstrates the CARTPT antibody detected the CARTPT protein (arrow).)
Rabbit anti-Mouse CARTPT Polyclonal Antibody | anti-CARTPT antibody
CARTPT Antibody (N-term)
IHC-P~~1:10~50
Western Blot (WB)
(CARTPT Antibody (N-term) (MBS9201884) western blot analysis in mouse heart tissue lysates(35ug/lane).This demonstrates the CARTPT antibody detected the CARTPT protein (arrow).)
Western Blot (WB)
(CARTPT Antibody (N-term) (MBS9201884) western blot analysis in mouse heart tissue lysates(35ug/lane).This demonstrates the CARTPT antibody detected the CARTPT protein (arrow).)
Immunohistochemistry (IHC)
(CARTPT Antibody (N-term) (MBS9201884) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CARTPT Antibody(N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CARTPT Antibody (N-term) (MBS9201884) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CARTPT Antibody(N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Busto, A., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(6):834-836(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Rigoli, L., et al. Acta Paediatr. 99(5):722-726(2010)
Vasseur, F., et al. J. Hum. Genet. 55(4):227-231(2010)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted protein which is processed by prohormone/proprotein convertases to produce smaller, biologically active peptides. Expression of the transcript for this gene is regulated by certain drugs such as cocaine, and the encoded protein is thought to be involved in the regulation of appetite and stress. Mutations in this gene are associated with susceptibility to obesity.[provided by RefSeq, Nov 2009]
Uniprot Description
CARTPT: Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. Belongs to the CART family.
Protein type: Hormone; Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q13.2
Cellular Component: extracellular space; secretory granule
Molecular Function: protein binding
Biological Process: negative regulation of osteoclast differentiation; activation of MAPKK activity; adult feeding behavior; signal transduction; cellular response to starvation; negative regulation of appetite; G-protein coupled receptor protein signaling pathway; synaptic transmission; cell-cell signaling; neuropeptide signaling pathway; positive regulation of epinephrine secretion; cell glucose homeostasis; circadian regulation of gene expression; negative regulation of bone resorption; regulation of insulin secretion; positive regulation of blood pressure; positive regulation of transmission of nerve impulse
Disease: Obesity
Research Articles on CARTPT
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Product Notes
The CARTPT cartpt (Catalog #AAA9201884) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 26-55. The CARTPT Antibody (N-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CARTPT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry Paraffin (IHC-P). WB~~1:1000 IHC-P~~1:10~50. Researchers should empirically determine the suitability of the CARTPT cartpt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CARTPT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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