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Western Blot (WB)

Rabbit Canstatin Polyclonal Antibody

Canstatin antibody

Reactivity
No cross reactivity with other proteins. (Reactivity with human, mouse, rat.)
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunohistochemistry
Purity
Canstatin antibody was purified by affinity chromatography
Synonyms
Canstatin; Polyclonal Antibody; Canstatin antibody; Polyclonal Canstatin; Anti-Canstatin; anti-Canstatin antibody
Ordering
 
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For Research Use Only!
Host
Rabbit
Reactivity
No cross reactivity with other proteins. (Reactivity with human, mouse, rat.)
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Canstatin antibody was purified by affinity chromatography
Form/Format
Lyophilized powder. Reconstitute with 200 ul distilled water for a final concentration of 500ug/ml in 5mg BSA, 0.9mg Na2HPO4, 0.5mg Thimerosal, and 0.05mg NaN3.
Concentration
100 ug, lyophilized (varies by lot)
Applicable Applications for anti-Canstatin antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F) Immunocytochemistry (ICC)
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
Immunogen
Canstatin antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human Canstatin, identical to the related rat and Rabbit sequences, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C, avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Lane 1: Rat Kidney Tissue Lysate)

Related Product Information for anti-Canstatin antibody
Affinity purified Rabbit polyclonal Canstatin antibody
Product Categories/Family for anti-Canstatin antibody

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Product Notes

The Canstatin (Catalog #AAA839081) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Canstatin antibody reacts with No cross reactivity with other proteins. (Reactivity with human, mouse, rat.) and may cross-react with other species as described in the data sheet. AAA Biotech's Canstatin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F) Immunocytochemistry (ICC). Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the Canstatin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Canstatin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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