Western Blot (WB)
(WB Suggested Anti-CAMK2G AntibodyTitration: 1.0 ug/mlPositive Control: THP-1 Whole Cell)
Rabbit CAMK2G Polyclonal Antibody | anti-CAMK2G antibody
CAMK2G antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-CAMK2G AntibodyTitration: 1.0 ug/mlPositive Control: THP-1 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-CAMK2G AntibodyTitration: 1.0 ug/mlPositive Control: THP-1 Whole Cell)
Target Description: The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.
NCBI and Uniprot Product Information
NCBI Description
The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]
Uniprot Description
CAMK2G: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.17; Protein kinase, CAMK; CAMK group; CAMK2 family
Chromosomal Location of Human Ortholog: 10q22
Cellular Component: nucleoplasm; sarcoplasmic reticulum membrane; membrane; plasma membrane; cytosol
Molecular Function: calmodulin binding; protein binding; protein homodimerization activity; calcium-dependent protein serine/threonine phosphatase activity; calmodulin-dependent protein kinase activity; ATP binding
Biological Process: nervous system development; synaptic transmission; dephosphorylation; regulation of skeletal muscle adaptation; insulin secretion; calcium ion transport; protein amino acid autophosphorylation; cytokine and chemokine mediated signaling pathway; regulation of calcium ion transport; cell differentiation; protein oligomerization; G1/S transition of mitotic cell cycle
Research Articles on CAMK2G
Similar Products
Product Notes
The CAMK2G camk2g (Catalog #AAA3215819) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAMK2G antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAMK2G can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CAMK2G camk2g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: TGNGSSVPEG RSSRDRTAPS AGMQPQPSLC SSAMRKQEII KITEQLIEAI. It is sometimes possible for the material contained within the vial of "CAMK2G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
