Rabbit CAMK2G Polyclonal Antibody | anti-CAMK2G antibody

CAMK2G Polyclonal Antibody

Cat. Num. AAA2561550

• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: CAMK2G; Polyclonal Antibody; CAMK2G Polyclonal Antibody; CaM kinase II; CaM kinase II gamma chain; CaM kinase II subunit gamma; CAMK; CAMK II; CaMK II subunit gamma; CAMKG; CAMKII; anti-CAMK2G antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.9mg/mL (varies by lot)
• Sequence Length: 558

• Applicable Applications for anti-CAMK2G antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:25-1:50; ELISA: 1:5000-1:10000
• Immunogen: Synthetic peptide of human CAMK2G
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CAMK2G Polyclonal Antibody at dilution of 1:30(×200))

Related Product Information for anti-CAMK2G antibody

The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.

Product Categories/Family for anti-CAMK2G antibody

Neuroscience; Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 62512173
• UniProt Accession #: Q13555
• NCBI Official Full Name: Calcium/calmodulin-dependent protein kinase type II subunit gamma
• UniProt Protein Name: Calcium/calmodulin-dependent protein kinase type II subunit gamma
• Protein Family: Calcium/calmodulin-dependent protein kinase
• UniProt Gene Name: CAMK2G
• UniProt Synonym Gene Names: CAMK; CAMK-II; CAMKG; CaM kinase II subunit gamma; CaMK-II subunit gamma
• UniProt Entry Name: KCC2G_HUMAN

Uniprot Description

CAMK2G: a protein kinase of the CAMK2 family. A prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses that may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. The holoenzyme is composed of four different chains: alpha, beta, gamma, and delta. The different chains assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. May interact with BAALC, MPDZ, SYN1 and synGAP. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.17; Protein kinase, CAMK; CAMK group; CAMK2 family

Chromosomal Location of Human Ortholog: 10q22

Cellular Component: nucleoplasm; sarcoplasmic reticulum membrane; membrane; plasma membrane; cytosol

Molecular Function: calmodulin binding; protein binding; protein homodimerization activity; calcium-dependent protein serine/threonine phosphatase activity; calmodulin-dependent protein kinase activity; ATP binding

Biological Process: nervous system development; synaptic transmission; dephosphorylation; regulation of skeletal muscle adaptation; insulin secretion; calcium ion transport; protein amino acid autophosphorylation; cytokine and chemokine mediated signaling pathway; regulation of calcium ion transport; cell differentiation; protein oligomerization; G1/S transition of mitotic cell cycle