Immunohistochemistry (IHC)
(Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human C4.4A Polyclonal Antibody
C4.4A (LYPD3, Y6/PLAUR domain containing 3 GPI-anchored metastasis-associated protein C4.4A homolog, Ly6/PLAUR domain-containing protein 3 precursor, Matrigel-induced gene C4 protein, MIG-C4, UNQ491/PRO1007)
Reactivity
Human
Applications
Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
C4.4A; Polyclonal Antibody; C4.4A (LYPD3; Y6/PLAUR domain containing 3 GPI-anchored metastasis-associated protein C4.4A homolog; Ly6/PLAUR domain-containing protein 3 precursor; Matrigel-induced gene C4 protein; MIG-C4; UNQ491/PRO1007); Anti -C4.4A (LYPD3; anti-C4.4A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human LYPD3.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide.
Applicable Applications for anti-C4.4A antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10-12.5ug/ml
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10-12.5ug/ml
Immunogen
Synthetic peptide corresponding to 14aa from the internal domain of human LYPD3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-C4.4A antibody
C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal keratinocytes of chronic wounds and the amniotic membrane of placenta. ISH analysis demonstrated expression in urothelium of the ureter. C4.4A expression has also been found to be upregulated in breast tumors when compare to normal breast tissue.
Product Categories/Family for anti-C4.4A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
C4.4A
Uniprot Description
LYPD3: Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
Protein type: Cell adhesion; Membrane protein, GPI anchor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19q13.31
Cellular Component: extracellular space; anchored to plasma membrane; integral to membrane
Molecular Function: laminin binding
Biological Process: cell-matrix adhesion
Similar Products
Product Notes
The C4.4A (Catalog #AAA645652) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C4.4A (LYPD3, Y6/PLAUR domain containing 3 GPI-anchored metastasis-associated protein C4.4A homolog, Ly6/PLAUR domain-containing protein 3 precursor, Matrigel-induced gene C4 protein, MIG-C4, UNQ491/PRO1007) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C4.4A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10-12.5ug/ml. Researchers should empirically determine the suitability of the C4.4A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C4.4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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