Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LYPD3 expression on PC-3 cells.)
Rabbit anti-Human LYPD3 Monoclonal Antibody | anti-LYPD3 antibody
Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal
Gene Names
LYPD3; C4.4A
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
LYPD3; Monoclonal Antibody; Recombinant Anti-LYPD3 Antibody (APC); Rabbit Monoclonal; C4.4A/LYPD3 Antibody (APC); Rabbit MAb; LY6/PLAUR domain containing 3; Anti-C4.4A Antibody; anti-LYPD3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
213
Specificity
Human C4.4A/LYPD3
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.03%ProClin300
Concentration
10ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-LYPD3 antibody
Flow Cytometry (FC/FACS/FCM)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human C4.4A/LYPD3 protein
Conjugation
APC
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human C4.4A/LYPD3 (rh C4.4A/LYPD3) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze!
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LYPD3 expression on PC-3 cells.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LYPD3 expression on PC-3 cells.)
Related Product Information for anti-LYPD3 antibody
Ly6/PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression
References
Smith B.A., et al., 2001, Cancer Res. 61:1678-85. Wuerfel J., et al., 2001, Gene 262:35-41. Clark H.F., et al., 2003, Genome Res. 13:2265-70. Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-85. Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-57.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,971 Da
NCBI Official Full Name
ly6/PLAUR domain-containing protein 3
NCBI Official Synonym Full Names
LY6/PLAUR domain containing 3
NCBI Official Symbol
LYPD3
NCBI Official Synonym Symbols
C4.4A
NCBI Protein Information
ly6/PLAUR domain-containing protein 3; MIG-C4; 2310061G07Rik; matrigel-induced gene C4 protein; GPI-anchored metastasis-associated protein homolog; GPI-anchored metastasis-associated protein C4.4A homolog
UniProt Protein Name
Ly6/PLAUR domain-containing protein 3
Protein Family
UniProt Gene Name
LYPD3
UniProt Synonym Gene Names
C4.4A; MIG-C4
UniProt Entry Name
LYPD3_HUMAN
Uniprot Description
LYPD3: Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Cell adhesion
Chromosomal Location of Human Ortholog: 19q13.31
Cellular Component: extracellular space; anchored to plasma membrane; integral to membrane
Molecular Function: laminin binding
Biological Process: cell-matrix adhesion
Research Articles on LYPD3
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Product Notes
The LYPD3 lypd3 (Catalog #AAA8105861) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-LYPD3 Antibody (APC), Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LYPD3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the LYPD3 lypd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LYPD3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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