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Rabbit C2orf60 Polyclonal Antibody | anti-C2orf60 antibody

C2orf60 antibody

Gene Names
TYW5; hTYW5; C2orf60
Applications
Western Blot
Synonyms
C2orf60; Polyclonal Antibody; C2orf60 antibody; Polyclonal C2orf60; Anti-C2orf60FLJ37953; Corf60 2; MGC70509; Corf60-2; anti-C2orf60 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
152
Applicable Applications for anti-C2orf60 antibody
Western Blot (WB)
Application Notes
WB: 0.2-1 ug/ml
Biological Significance
C2orf60 is Involved in cell differentiation and/or proliferation.
Cross-Reactivity
Human, Rat, Mouse, Dog
Immunogen
C2orf60 antibody was raised in rabbit using the middle region of C2ORF60 as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-C2orf60 antibody
Affinity purified rabbit polyclonal C2orf60 antibody
Product Categories/Family for anti-C2orf60 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
17,526 Da
NCBI Official Full Name
C2orf60 protein
NCBI Official Synonym Full Names
tRNA-yW synthesizing protein 5
NCBI Official Symbol
TYW5
NCBI Official Synonym Symbols
hTYW5; C2orf60
NCBI Protein Information
tRNA wybutosine-synthesizing protein 5
UniProt Protein Name
tRNA wybutosine-synthesizing protein 5
UniProt Gene Name
TYW5
UniProt Synonym Gene Names
C2orf60; hTYW5
UniProt Entry Name
TYW5_HUMAN

Uniprot Description

TYW5: tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes. Belongs to the TYW5 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.11.42

Chromosomal Location of Human Ortholog: 2q33.1

Molecular Function: protein homodimerization activity; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; tRNA binding

Biological Process: wybutosine biosynthetic process

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Product Notes

The C2orf60 tyw5 (Catalog #AAA839012) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's C2orf60 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.2-1 ug/ml. Researchers should empirically determine the suitability of the C2orf60 tyw5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C2orf60, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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