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Western Blot (WB) (BRWD2 Antibody (Center) western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the BRWD2 antibody detected BRWD2 protein (arrow).)

Rabbit anti-Human, Mouse BRWD2 Polyclonal Antibody | anti-BRWD2 antibody

BRWD2, ID (WDR11, BRWD2, KIAA1351, WDR15, WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15) (Biotin)

Gene Names
WDR11; DR11; HH14; BRWD2; WDR15
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
BRWD2; Polyclonal Antibody; ID (WDR11; KIAA1351; WDR15; WD repeat-containing protein 11; Bromodomain and WD repeat-containing protein 2; WD repeat-containing protein 15) (Biotin); WDR11; WD repeat-containing protein 15; anti-BRWD2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-BRWD2 antibody
Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB)
Application Notes
FC/FACS: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
BRWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-580 amino acids from the Central region of human BRWD2.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(BRWD2 Antibody (Center) western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the BRWD2 antibody detected BRWD2 protein (arrow).)

Western Blot (WB) (BRWD2 Antibody (Center) western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the BRWD2 antibody detected BRWD2 protein (arrow).)

Flow Cytometry (FC/FACS)

(BRWD2 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (BRWD2 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-BRWD2 antibody
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Product Categories/Family for anti-BRWD2 antibody
References
Katoh, M., et al. Int. J. Mol. Med. 11(5):579-583(2003). Katoh, M., et al. Int. J. Oncol. 22(5):1155-1159(2003). Chernova, O.B., et al. Oncogene 20(38):5378-5392(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
136,685 Da
NCBI Official Full Name
WD repeat-containing protein 11
NCBI Official Synonym Full Names
WD repeat domain 11
NCBI Official Symbol
WDR11
NCBI Official Synonym Symbols
DR11; HH14; BRWD2; WDR15
NCBI Protein Information
WD repeat-containing protein 11; WD repeat domain 15; WD repeat-containing protein 15; bromodomain and WD repeat-containing protein 2
UniProt Protein Name
WD repeat-containing protein 11
UniProt Gene Name
WDR11
UniProt Synonym Gene Names
BRWD2; KIAA1351; WDR15
UniProt Entry Name
WDR11_HUMAN

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Product Notes

The BRWD2 wdr11 (Catalog #AAA6279035) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BRWD2, ID (WDR11, BRWD2, KIAA1351, WDR15, WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15) (Biotin) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BRWD2 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB). FC/FACS: 1:10-50 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the BRWD2 wdr11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BRWD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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