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SDS-Page (Gel: 6%SDS-PAGE Lysate: 40 ug, Lane: Hela cell lysate, Primary antibody:WDR11 antibody at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 50 seconds)

Rabbit anti-Human WDR11 Polyclonal Antibody | anti-WDR11 antibody

WDR11 Antibody

Gene Names
WDR11; DR11; HH14; SRI1; BRWD2; WDR15
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification
Synonyms
WDR11; Polyclonal Antibody; WDR11 Antibody; DR11; HH14; BRWD2; WDR15; anti-WDR11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total WDR11 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.6mg/ml (varies by lot)
Sequence Length
1224
Applicable Applications for anti-WDR11 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
Western Blot: 1:200-1000
Immunohistochemistry: 1: 20-100
Immunogen
Synthetic peptide of human WDR11
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

SDS-Page

(Gel: 6%SDS-PAGE Lysate: 40 ug, Lane: Hela cell lysate, Primary antibody:WDR11 antibody at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 50 seconds)

SDS-Page (Gel: 6%SDS-PAGE Lysate: 40 ug, Lane: Hela cell lysate, Primary antibody:WDR11 antibody at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 50 seconds)

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using WDR11 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using WDR11 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using WDR11 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using WDR11 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-WDR11 antibody
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Product Categories/Family for anti-WDR11 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
136,685 Da
NCBI Official Full Name
WD repeat-containing protein 11
NCBI Official Synonym Full Names
WD repeat domain 11
NCBI Official Symbol
WDR11
NCBI Official Synonym Symbols
DR11; HH14; SRI1; BRWD2; WDR15
NCBI Protein Information
WD repeat-containing protein 11
UniProt Protein Name
WD repeat-containing protein 11
UniProt Gene Name
WDR11
UniProt Synonym Gene Names
BRWD2; KIAA1351; WDR15
UniProt Entry Name
WDR11_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]

Uniprot Description

BRWD2: a protein with two WD40 domains. A translocation of BRWD2 with ZNF320 is found in a form of glioblastoma (t(10;19)(q26;q13.3)).

Protein type: Membrane protein, integral; Oncoprotein

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: cytoplasm; lysosomal membrane; membrane; microtubule cytoskeleton

Molecular Function: protein binding

Disease: Hypogonadotropic Hypogonadism 14 With Or Without Anosmia

Research Articles on WDR11

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Product Notes

The WDR11 wdr11 (Catalog #AAA9417395) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WDR11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's WDR11 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Western Blot: 1:200-1000 Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the WDR11 wdr11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WDR11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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