Mucosae Associated Epithelia Chemokine (MEC) Recombinant Protein | MEC recombinant protein

Recombinant Mucosae Associated Epithelia Chemokine (MEC)

Cat. Num. AAA2012326

• Gene Names: Ccl28; MEC; CCK1; Scya28
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Mucosae Associated Epithelia Chemokine (MEC); Recombinant Mucosae Associated Epithelia Chemokine (MEC); MEC recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- FQTS EAILPMASSC CTEVSHHVSG RLLERVSSCS IQRADGDCDL AAVILHVKRR RICISPHNRT LKQWMRASEV KKNGRENVCS GKKQPSRKDR KGHTTRKHRT RGTHRHEASR
• Sequence Length: 130

• Applicable Applications for MEC recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Phe17~Arg130 (Accession # Q9JIL2) with two N-terminal Tags, His-tag and T7-tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 9931984
• NCBI GeneID: 56838
• NCBI Accession #: NP_064675.1
• NCBI GenBank Nucleotide #: NM_020279.3
• UniProt Accession #: Q9JIL2
• Molecular Weight: 16.8kDa
• NCBI Official Full Name: C-C motif chemokine 28
• NCBI Official Synonym Full Names: chemokine (C-C motif) ligand 28
• NCBI Official Symbol: Ccl28
• NCBI Official Synonym Symbols: MEC; CCK1; Scya28
• NCBI Protein Information: C-C motif chemokine 28; small inducible cytokine A28; small-inducible cytokine A28
• UniProt Protein Name: C-C motif chemokine 28
• Protein Family: CysO-cysteine peptidase
• UniProt Gene Name: Ccl28
• UniProt Synonym Gene Names: Scya28
• UniProt Entry Name: CCL28_MOUSE

Uniprot Description

CCL28: Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Chemokine; Secreted

Cellular Component: extracellular space; cell; extracellular region; cytosol

Molecular Function: chemokine activity; cytokine activity

Biological Process: elevation of cytosolic calcium ion concentration; immune response; positive regulation of cell-matrix adhesion; chemotaxis