Rabbit anti-Human BDKRB1 Polyclonal Antibody | anti-BDKRB1 antibody

BDKRB1 (B1 Bradykinin Receptor, BK-1 Receptor, B1R, BRADYB1) (Biotin)

Cat. Num. AAA6371191

• Gene Names: BDKRB1; B1R; BKR1; B1BKR; BKB1R; BDKRB2; BRADYB1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: BDKRB1; Polyclonal Antibody; BDKRB1 (B1 Bradykinin Receptor; BK-1 Receptor; B1R; BRADYB1) (Biotin); anti-BDKRB1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human BDKRB1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-BDKRB1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human BDKRB1, aa1-353 (AAH34705).
• Immunogen Sequence: LASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of BDKRB1 expression in transfected 293T cell line by BDKRB1 polyclonal antibody. Lane 1: BDKRB1 transfected lysate (38.94kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-BDKRB1 antibody

Bradykinin B1 receptor is generally only minimally expressed under normal physiological conditions, but the expression is induced rapidly under pathologic conditions such as ischemia, atheromatous disease, or exposure to inflammatory cytokines. Expression has been reported in brain, colon, kidney, lung, nasal mucosa, pancreas, prostate, skin, spinal cord, and vessel. ESTs have been isolated from normal human connective tissue libraries and in human kidney and skin cancer libraries.

Product Categories/Family for anti-BDKRB1 antibody

Antibodies; Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 21961598
• NCBI GeneID: 623
• Molecular Weight: 40,495 Da
• NCBI Official Full Name: Homo sapiens bradykinin receptor B1, mRNA
• NCBI Official Synonym Full Names: bradykinin receptor B1
• NCBI Official Symbol: BDKRB1
• NCBI Official Synonym Symbols: B1R; BKR1; B1BKR; BKB1R; BDKRB2; BRADYB1
• NCBI Protein Information: B1 bradykinin receptor
• Protein Family: B1 bradykinin receptor

NCBI Description

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]