Western Blot (WB)
(Western Blot analysis of BCL2L15 in Mouse small intestines tissue lysate using BCL2L15 Rabbit pAb at dilution 1/750)
Rabbit anti-Human, Mouse BCL2L15 Polyclonal Antibody | anti-BCL2L15 antibody
BCL2L15 Rabbit pAb
Gene Names
BCL2L15; Bfk; C1orf178
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
BCL2L15; Polyclonal Antibody; BCL2L15 Rabbit pAb; BCL2 like 15; Bfk; C1orf178; anti-BCL2L15 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.9mg/ml (varies by lot)
Applicable Applications for anti-BCL2L15 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:50-1:200
IHC-P: 1:50-1:200
Immunogen
Fusion protein of human BCL2L15
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of BCL2L15 in Mouse small intestines tissue lysate using BCL2L15 Rabbit pAb at dilution 1/750)
Western Blot (WB)
(Western Blot analysis of BCL2L15 in Mouse small intestines tissue lysate using BCL2L15 Rabbit pAb at dilution 1/750)
Immunohistochemistry (IHC)
(Immunohistochemistry of BCL2L15 in paraffin-embedded Human liver cancer tissue using BCL2L15 Rabbit pAb at dilution 1/50. Predicted cell location: Cytoplasm)
Immunohistochemistry (IHC)
(Immunohistochemistry of BCL2L15 in paraffin-embedded Human liver cancer tissue using BCL2L15 Rabbit pAb at dilution 1/50. Predicted cell location: Cytoplasm)
Related Product Information for anti-BCL2L15 antibody
Proteins of the Bcl-2 family are critical regulators of apoptosis. Proapoptotic members, like Bax, contain three of the four Bcl-2 homology regions (BH1-3), while BH3-only proteins, like Bim, possess only the short BH3 motif. Database searches revealed Bfk, an unusual novel member of the Bcl-2 family that contains a BH2 and BH3 region but not BH1 or BH4. Bfk is thus most closely related to Bcl-G(L). It lacks a C-terminal membrane anchor and is cytosolic. Enforced expression of Bfk weakly promoted apoptosis and antagonized Bcl-2's prosurvival function. Like Bcl-G(L), Bfk did not bind to any Bcl-2 family members, even though its BH3 motif can mediate association with prosurvival proteins. Low amounts of Bfk were found in stomach, ovary, bone marrow and spleen, but its level in the mammary gland rose markedly during pregnancy, suggesting that Bfk may play a role in mammary development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
163
NCBI Official Full Name
Bcl-2-like protein 15
NCBI Official Synonym Full Names
BCL2-like 15
NCBI Official Symbol
BCL2L15
NCBI Official Synonym Symbols
Bfk; C1orf178
NCBI Protein Information
bcl-2-like protein 15; bcl2-L-15; pro-apoptotic Bcl-2 protein
UniProt Protein Name
Bcl-2-like protein 15
Protein Family
UniProt Gene Name
BCL2L15
UniProt Synonym Gene Names
C1orf178; Bcl2-L-15
UniProt Entry Name
B2L15_HUMAN
Uniprot Description
BCL2L15: 2 isoforms of the human protein are produced by alternative splicing
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 1p13.2
Cellular Component: cytosol; nucleus
Biological Process: apoptosis
Research Articles on BCL2L15
Similar Products
Product Notes
The BCL2L15 bcl2l15 (Catalog #AAA4759904) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL2L15 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BCL2L15 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the BCL2L15 bcl2l15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL2L15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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