Rabbit ATP6V1G1 / ATP6J Polyclonal Antibody | anti-ATP6V1G1 antibody

Anti-ATP6V1G1 / ATP6J Antibody IHC-plus

Cat. Num. AAA2400405

• Gene Names: ATP6V1G1; ATP6G; ATP6J; Vma10; ATP6G1; ATP6GL
• Reactivity: Mouse, Rat, Human
• Applications: Immunohistochemistry, ELISA
• Purity: Caprylic acid and ammonium sulfate precipitation
• Synonyms: ATP6V1G1 / ATP6J; Polyclonal Antibody; Anti-ATP6V1G1 / ATP6J Antibody IHC-plus; Rabbit Polyclonal (IgG) to Human ATP6V1G1 / ATP6J; Human ATP6V1G1 / ATP6J; ATP6GL; Atp1v1g1; ATP6G; ATP6G1; V-ATPase 13 kDa subunit 1; V-ATPase G subunit 1; Vma10; V-ATPase subunit G 1; anti-ATP6V1G1 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat, Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human ATP6V1G1 / ATP6J
• Purity/Purification: Caprylic acid and ammonium sulfate precipitation
• Form/Format: PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
• Sequence Length: 118

• Applicable Applications for anti-ATP6V1G1 antibody: Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
• Application Notes: IHC-P (10 ug/ml)
• Immunogen: ATP6V1G1 / ATP6J antibody was raised against recombinant human V-type proton ATPase subunit G 1 protein.
• Immunogen Description: Recombinant human V-type proton ATPase subunit G 1 protein.
• Immunogen Type: Recombinant protein
• Target Species: Human
• Preparation and Storage: Aliquot and store at -20 degree C or -80 degree C. Avoid freeze-thaw cycles.

Immunohistochemistry - Paraffin (IHC)

(Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC)

(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Related Product Information for anti-ATP6V1G1 antibody

ATP6V1G1 Antibody, ATP6GL Antibody, ATP6J Antibody, Atp1v1g1 Antibody, ATP6G Antibody, ATP6G1 Antibody, V-ATPase 13 kDa subunit 1 Antibody, V-ATPase G subunit 1 Antibody, Vma10 Antibody, V-ATPase subunit G 1 Antibody Description: ATP6V1G1 / ATP6J is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain.

NCBI and Uniprot Product Information

• NCBI GI #: 4757818
• NCBI GeneID: 9550
• NCBI Accession #: NP_004879.1
• NCBI GenBank Nucleotide #: NM_004888.3
• UniProt Accession #: O75348; Q6IB33
• Molecular Weight: 13,758 Da
• NCBI Official Full Name: V-type proton ATPase subunit G 1
• NCBI Official Synonym Full Names: ATPase H+ transporting V1 subunit G1
• NCBI Official Symbol: ATP6V1G1
• NCBI Official Synonym Symbols: ATP6G; ATP6J; Vma10; ATP6G1; ATP6GL
• NCBI Protein Information: V-type proton ATPase subunit G 1
• UniProt Protein Name: V-type proton ATPase subunit G 1
• Protein Family: V-type proton ATPase
• UniProt Gene Name: ATP6V1G1
• UniProt Synonym Gene Names: ATP6G; ATP6G1; ATP6J; V-ATPase subunit G 1
• UniProt Entry Name: VATG1_HUMAN

NCBI Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP6V1G1: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase G subunit family.

Protein type: Vesicle; Hydrolase

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: cytosol; lysosomal membrane; plasma membrane; vacuolar proton-transporting V-type ATPase complex

Molecular Function: ATPase binding; hydrogen-exporting ATPase activity, phosphorylative mechanism; protein binding

Biological Process: cell redox homeostasis; cellular iron ion homeostasis; insulin receptor signaling pathway; metabolic process; transferrin transport; transmembrane transport