SDS-PAGE
(SDS-PAGE Analysis Purified Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R). Confirmation of Purity and Integrity of Antibody.)
Rabbit Tenascin C Monoclonal Antibody | anti-TNC antibody
Tenascin C (Stromal Marker For Epithelial Malignancy)
Gene Names
TNC; GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225
Reactivity
Human.Does not react with rat. Others not known.
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
Tenascin C, Antibody; Tenascin C (Stromal Marker For Epithelial Malignancy); Cytotactin; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; Hexabrachion (HXB); JI; Myotendinous antigen; Neuronectin; TNC; anti-TNC antibody
Host
Rabbit
Reactivity
Human.
Does not react with rat. Others not known.
Does not react with rat. Others not known.
Clonality
Monoclonal
Isotype
IgG
Clone Number
TNC/2981R
Specificity
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
1,746
Applicable Applications for anti-TNC antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant full-length human TNC protein
Positive Control
Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell, and lung carcinomas. Staining of normal fibroblasts serves as internal positive control.
Cellular Localization
Connective tissue matrix
Chromosome Location
9q33
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R). Confirmation of Purity and Integrity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Tenascin C Rabbit Recombinant Monoclonal Antibody (TNC/2981R).)
Related Product Information for anti-TNC antibody
Recombinant Rabbit Monoclonal Antibody
References
Verstraeten AA, et. al. British Journal of Dermatology, 1992, 127(6):571-4.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
210kDa; 300kDa
NCBI Official Full Name
tenascin
NCBI Official Synonym Full Names
tenascin C
NCBI Official Symbol
TNC
NCBI Official Synonym Symbols
GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225
NCBI Protein Information
tenascin
UniProt Protein Name
Tenascin
UniProt Gene Name
TNC
UniProt Synonym Gene Names
HXB; TN; TN-C
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Product Notes
The TNC tnc (Catalog #AAA214760) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Tenascin C (Stromal Marker For Epithelial Malignancy) reacts with Human. Does not react with rat. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's Tenascin C can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TNC tnc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tenascin C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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