Rabbit ATP6V1G1 Polyclonal Antibody | anti-ATP6V1G1 antibody

ATP6V1G1 Rabbit Polyclonal

Cat. Num. AAA766957

• Gene Names: ATP6V1G1; ATP6G; ATP6J; Vma10; ATP6G1; ATP6GL
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ATP6V1G1; Polyclonal Antibody; ATP6V1G1 Rabbit Polyclonal; anti-ATP6V1G1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 118

• Applicable Applications for anti-ATP6V1G1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS766957 (ATP6V1G1 antibody) at dilution of 1:100)

Western Blot (WB)

(Jurkat cells were subjected to SDS PAGE followed by western blot with MBS766957 (ATP6V1G1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 49457468
• NCBI GeneID: 9550
• UniProt Accession #: Q6IB33; O75348
• Molecular Weight: 13,758 Da
• NCBI Official Full Name: ATP6V1G1, partial
• NCBI Official Synonym Full Names: ATPase H+ transporting V1 subunit G1
• NCBI Official Symbol: ATP6V1G1
• NCBI Official Synonym Symbols: ATP6G; ATP6J; Vma10; ATP6G1; ATP6GL
• NCBI Protein Information: V-type proton ATPase subunit G 1
• UniProt Protein Name: V-type proton ATPase subunit G 1
• Protein Family: V-type proton ATPase
• UniProt Gene Name: ATP6V1G1
• UniProt Synonym Gene Names: ATP6G; ATP6G1; ATP6J; V-ATPase subunit G 1
• UniProt Entry Name: VATG1_HUMAN

NCBI Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ATP6V1G1: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase G subunit family.

Protein type: Vesicle; Hydrolase

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: cytosol; lysosomal membrane; plasma membrane; vacuolar proton-transporting V-type ATPase complex

Molecular Function: ATPase binding; hydrogen-exporting ATPase activity, phosphorylative mechanism; protein binding

Biological Process: insulin receptor signaling pathway; metabolic process; regulation of macroautophagy; transferrin transport