Rabbit anti-Human ATP5G2 Polyclonal Antibody | anti-ATP5G2 antibody

Rabbit Polyclonal (IgG) to Human ATP5G2

Cat. Num. AAA242715

• Gene Names: ATP5G2; ATP5A
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: ATP5G2; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human ATP5G2; Anti-ATP5G2 Antibody (aa1-50) IHC-plus; ATPase protein 9; ATPase subunit c; ATP synthase c subunit; ATP synthase proteolipid P2; ATP5A; ATPase protein 9 isoform 2; ATPase subunit C isoform 2; Human ATP5G2; anti-ATP5G2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ATP5G2 Antibody detects endogenous levels of total ATP5G2 protein.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 198

• Applicable Applications for anti-ATP5G2 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:40000), IHC-P (5 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic peptide from human ATP5G2 (aa1-50).
• Immunogen: ATP5G2 antibody was raised against synthetic peptide from human ATP5G2 (aa1-50).
• Antigen Modification: aa1-50
• Preparation and Storage: Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-ATP5G2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-ATP5G2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Product Categories/Family for anti-ATP5G2 antibody

Family: Transporter; Subfamily: ATPase - F type

NCBI and Uniprot Product Information

• NCBI GI #: 85794840
• NCBI GeneID: 517
• NCBI Accession #: NP_005167.2
• NCBI GenBank Nucleotide #: NM_005176.5
• UniProt Accession #: Q06055; B3KQQ6
• Molecular Weight: 16,334 Da
• NCBI Official Full Name: ATP synthase F(0) complex subunit C2, mitochondrial isoform b
• NCBI Official Synonym Full Names: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
• NCBI Official Symbol: ATP5G2
• NCBI Official Synonym Symbols: ATP5A
• NCBI Protein Information: ATP synthase F(0) complex subunit C2, mitochondrial; ATP synthase F(0) complex subunit C2, mitochondrial; ATPase protein 9; ATPase subunit C; ATP synthase c subunit; ATP synthase proteolipid P2; ATP synthase lipid-binding protein, mitochondrial; mitochondrial ATP synthase, subunit C (subunit 9), isoform 2; ATP synthase proton-transporting mitochondrial F(0) complex subunit C2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9); ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2
• UniProt Protein Name: ATP synthase F(0) complex subunit C2, mitochondrial
• UniProt Gene Name: ATP5G2
• UniProt Entry Name: AT5G2_HUMAN

NCBI Description

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene has multiple pseudogenes. [provided by RefSeq, Jun 2010]

Uniprot Description

ATP5G2: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. Belongs to the ATPase C chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: mitochondrial outer membrane; proton-transporting ATP synthase complex, coupling factor F(o); integral to membrane; mitochondrial proton-transporting ATP synthase complex

Molecular Function: transporter activity; hydrogen ion transmembrane transporter activity; lipid binding

Biological Process: cellular metabolic process; response to ethanol; ATP hydrolysis coupled proton transport; mitochondrial ATP synthesis coupled proton transport