Rabbit anti-Human ATP5G2 Polyclonal Antibody | anti-ATP5G2 antibody

ATP5G2-Specific Rabbit Polyclonal

Cat. Num. AAA766940

• Gene Names: ATP5G2; ATP5A
• Reactivity: Human
• Applications: ELISA, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ATP5G2; Polyclonal Antibody; ATP5G2-Specific Rabbit Polyclonal; anti-ATP5G2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 141

• Applicable Applications for anti-ATP5G2 antibody: ELISA (EIA), Immunoprecipitation (IP)
• Immunogen: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Testing Data

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NCBI and Uniprot Product Information

• NCBI GI #: 18088565
• NCBI GeneID: 517
• Molecular Weight: 16,334 Da
• NCBI Official Full Name: ATP5G2 protein
• NCBI Official Synonym Full Names: ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)
• NCBI Official Symbol: ATP5G2
• NCBI Official Synonym Symbols: ATP5A
• NCBI Protein Information: ATP synthase F(0) complex subunit C2, mitochondrial
• UniProt Protein Name: ATP synthase F(0) complex subunit C2, mitochondrial
• UniProt Gene Name: ATP5G2
• UniProt Entry Name: AT5G2_HUMAN

NCBI Description

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene has multiple pseudogenes. [provided by RefSeq, Jun 2010]

Uniprot Description

ATP5G2: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. Belongs to the ATPase C chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrial proton-transporting ATP synthase complex; proton-transporting ATP synthase complex, coupling factor F(o)

Molecular Function: hydrogen ion transmembrane transporter activity; lipid binding; transporter activity

Biological Process: ATP biosynthetic process; ATP hydrolysis coupled proton transport; mitochondrial ATP synthesis coupled proton transport