Rabbit anti-Human ASB11 Polyclonal Antibody | anti-ASB11 antibody

ASB11 Antibody

Cat. Num. AAA7005359

• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: >95%,Protein G purified
• Synonyms: ASB11; Polyclonal Antibody; ASB11 Antibody; Ankyrin repeat and SOCS box protein 11; ASB-11; anti-ASB11 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 302

• Applicable Applications for anti-ASB11 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Immunogen: Recombinant human Ankyrin repeat and SOCS box protein 11 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47803 / sc-47801
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7005359 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human breast cancer using MBS7005359 at dilution of 1:100)

Related Product Information for anti-ASB11 antibody

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 60218887
• NCBI GeneID: 140456
• NCBI Accession #: NP_001012428.1
• NCBI GenBank Nucleotide #: NM_001012428.2
• UniProt Accession #: Q8WXH4; Q3SYC4; Q7Z667; E9PEN1
• Molecular Weight: 32,952 Da
• NCBI Official Full Name: ankyrin repeat and SOCS box protein 11 isoform b
• NCBI Official Synonym Full Names: ankyrin repeat and SOCS box containing 11
• NCBI Official Symbol: ASB11
• NCBI Protein Information: ankyrin repeat and SOCS box protein 11
• UniProt Protein Name: Ankyrin repeat and SOCS box protein 11
• Protein Family: Ankyrin repeat and SOCS box protein
• UniProt Gene Name: ASB11
• UniProt Synonym Gene Names: ASB-11
• UniProt Entry Name: ASB11_HUMAN

NCBI Description

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Uniprot Description

ASB11: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: Xp22.31

Cellular Component: intracellular

Biological Process: protein ubiquitination