Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (ARIH1 Antibody) at dilution 1/30.)
Rabbit anti-Human, Mouse ARIH1 Polyclonal Antibody | anti-ARIH1 antibody
ARIH1 Antibody
Gene Names
ARIH1; ARI; HARI; HHARI; UBCH7BP
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ARIH1; Polyclonal Antibody; ARIH1 Antibody; ARI; HARI; HHARI; UBCH7BP; anti-ARIH1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.9mg/mL (varies by lot)
Applicable Applications for anti-ARIH1 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
Synthetic peptide of human ARIH1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (ARIH1 Antibody) at dilution 1/30.)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (ARIH1 Antibody) at dilution 1/30.)
Related Product Information for anti-ARIH1 antibody
ARIH1 (ariadne homolog), also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI (human homolog of Drosophila ariadne), MOP-6 (monocyte protein 6) or UBCH7BP (UBCH7 binding protein), is a 557 amino acid cytoplasmic protein. Expressed in a wide variety of tissues, ARIH1 contains two RING-type zinc fingers and one IBR (in-between RING fingers)-type domain. ARIH1 is believed to be involved in protein degradation and protein translation. ARIH1 interacts with UBCH7 and is thought to function as an E3 ubiquitin-protein ligase (or as a component of an E3 complex) that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme (UBCH7) and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, ARIH1 interacts with and polyubiquitylates eIF4E2, thereby targeting it for proteasomal degradation.
Product Categories/Family for anti-ARIH1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61kDa
NCBI Official Full Name
E3 ubiquitin-protein ligase ARIH1
NCBI Official Synonym Full Names
ariadne RBR E3 ubiquitin protein ligase 1
NCBI Official Symbol
ARIH1
NCBI Official Synonym Symbols
ARI; HARI; HHARI; UBCH7BP
NCBI Protein Information
E3 ubiquitin-protein ligase ARIH1
UniProt Protein Name
Kelch repeat and BTB domain-containing protein 8
Protein Family
UniProt Gene Name
KBTBD8
UniProt Synonym Gene Names
KIAA1842; TAKRP; TA-KRP
Uniprot Description
KBTBD8: 2 isoforms of the human protein are produced by alternative splicing
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 3p14.1
Molecular Function: ubiquitin-protein ligase activity
Research Articles on ARIH1
Similar Products
Product Notes
The ARIH1 kbtbd8 (Catalog #AAA9434783) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARIH1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ARIH1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the ARIH1 kbtbd8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARIH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
