Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovary tissue slide using MBS766782 (ARHGAP21 Antibody) at dilution of 1:50)
Rabbit anti-Human, Rat ARHGAP21 Polyclonal Antibody | anti-ARHGAP21 antibody
ARHGAP21 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovary tissue slide using MBS766782 (ARHGAP21 Antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovary tissue slide using MBS766782 (ARHGAP21 Antibody) at dilution of 1:50)
Western Blot (WB)
(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS766782 (ARHGAP21 Antibody) at dilution of 1:600)
Western Blot (WB)
(PC-3 cells were subjected to SDS PAGE followed by western blot with MBS766782 (ARHGAP21 Antibody) at dilution of 1:600)
NCBI and Uniprot Product Information
NCBI Description
ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]
Uniprot Description
ARHGAP21: Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 10p12.1|10p12.3
Cellular Component: cell junction; cytoplasmic vesicle membrane; cytoskeleton; Golgi apparatus; Golgi membrane
Molecular Function: GTPase activator activity; protein binding
Biological Process: establishment of Golgi localization; Golgi organization and biogenesis; maintenance of Golgi localization; positive regulation of GTPase activity; signal transduction
Research Articles on ARHGAP21
Similar Products
Product Notes
The ARHGAP21 arhgap21 (Catalog #AAA766782) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARHGAP21 Rabbit Polyclonal reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP21 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ARHGAP21 arhgap21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGAP21, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
