Western Blot (WB)
(AP1G2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the AP1G2 antibody detected the AP1G2 protein (arrow).)
Rabbit anti-Human AP1G2 Polyclonal Antibody | anti-AP1G2 antibody
AP1G2 Antibody (N-term)
Western Blot (WB)
(AP1G2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the AP1G2 antibody detected the AP1G2 protein (arrow).)
Western Blot (WB)
(AP1G2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the AP1G2 antibody detected the AP1G2 protein (arrow).)
vesicles transporting ligand-receptor complexes from the plasma
membrane or from the trans-Golgi network to lysosomes. The adaptin
family of proteins is compsed of four classes of molecules named
alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together
with medium and small subunits, form a heterotetrameric complex
called an adaptor, whose role is to promote the formation of
clathrin-coated pits and vesicles. The protein encoded by this gene
is a gamma-adaptin protein and it belongs to the adaptor complexes
large subunits family. This protein along with the complex is
thought to function at some trafficking step in the complex
pathways between the trans-Golgi network and the cell surface.
There are two alternatively spliced transcript variants of this
gene encoding the same protein.
Rost, M., et al. J. Biol. Chem. 283(46):32119-32130(2008)
Lambert, C., et al. J. Virol. 81(17):9050-9060(2007)
Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
Mattera, R., et al. J. Biol. Chem. 279(9):8018-8028(2004)
NCBI and Uniprot Product Information
NCBI Description
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
Uniprot Description
AP1G2: May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV). Belongs to the adaptor complexes large subunit family.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: Golgi apparatus; transport vesicle; AP-1 adaptor complex; membrane; Golgi-associated vesicle; endosome membrane
Molecular Function: protein binding; protein transporter activity
Biological Process: vesicle-mediated transport; intracellular protein transport; viral reproduction
Research Articles on AP1G2
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Product Notes
The AP1G2 ap1g2 (Catalog #AAA9214909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The AP1G2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AP1G2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AP1G2 ap1g2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AP1G2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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