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Immunohistochemistry (IHC) (Human Placenta (formalin-fixed, paraffin-embedded) stained with ANXA11 antibody at 3.75ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Goat anti-Human ANXA11 Polyclonal Antibody | anti-ANXA11 antibody

ANXA11, NT (Annexin A11, Annexin-11, Annexin XI, Calcyclin-associated Annexin 50, CAP-50, 56kD Autoantigen, ANX11)

Gene Names
ANXA11; ANX11; CAP50
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
ANXA11; Polyclonal Antibody; NT (Annexin A11; Annexin-11; Annexin XI; Calcyclin-associated Annexin 50; CAP-50; 56kD Autoantigen; ANX11); Anti -ANXA11; anti-ANXA11 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human ANXA11.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Applicable Applications for anti-ANXA11 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:32,000
Western Blot: 0.2-1ug/ml
Immunohistochemistry (Formalin-fixed, paraffin-embedded): 3.75ug/ml
Immunogen
Synthetic peptide corresponding to YPGYPPPPGGYPP-C from the N-terminal of human ANXA11.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Placenta (formalin-fixed, paraffin-embedded) stained with ANXA11 antibody at 3.75ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC) (Human Placenta (formalin-fixed, paraffin-embedded) stained with ANXA11 antibody at 3.75ug/ml followed by biotinylated goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Western Blot (WB)

(Antibody staining (0.2ug/ml) of HeLa lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)

Western Blot (WB) (Antibody staining (0.2ug/ml) of HeLa lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
Related Product Information for anti-ANXA11 antibody
This protein is a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 54kD antigen recognized by sera from patients with various autoimmune diseases. Transcript variants encoding the same isoform have been identified.
Product Categories/Family for anti-ANXA11 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
311
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,390 Da
NCBI Official Full Name
annexin A11 isoform 1
NCBI Official Synonym Full Names
annexin A11
NCBI Official Symbol
ANXA11
NCBI Official Synonym Symbols
ANX11; CAP50
NCBI Protein Information
annexin A11; CAP-50; annexin XI; annexin-11; 56 kDa autoantigen; autoantigen, 56-kD; calcyclin-associated annexin 50
UniProt Protein Name
Annexin A11
Protein Family
UniProt Gene Name
ANXA11
UniProt Synonym Gene Names
ANX11; CAP-50
UniProt Entry Name
ANX11_HUMAN

NCBI Description

This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, May 2013]

Uniprot Description

ANXA11: a calcium/phospholipid-binding protein found throughout the nucleoplasm at interphase and at the mitotic phase is concentrated at the loop-like structure around the mitotic apparatus. May interact with calcyclin (S100A6) in vivo. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding; Nuclear envelope; Lipid-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q23

Cellular Component: nucleoplasm; specific granule; azurophil granule; membrane; cytoplasm; melanosome; nuclear envelope; spindle; midbody; phagocytic vesicle

Molecular Function: protein binding; calcium-dependent phospholipid binding; phosphatidylethanolamine binding; calcium ion binding; calcium-dependent protein binding

Biological Process: response to calcium ion; phagocytosis

Research Articles on ANXA11

Similar Products

Product Notes

The ANXA11 anxa11 (Catalog #AAA642614) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The ANXA11, NT (Annexin A11, Annexin-11, Annexin XI, Calcyclin-associated Annexin 50, CAP-50, 56kD Autoantigen, ANX11) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ANXA11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: ELISA: 1:32,000 Western Blot: 0.2-1ug/ml Immunohistochemistry (Formalin-fixed, paraffin-embedded): 3.75ug/ml. Researchers should empirically determine the suitability of the ANXA11 anxa11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANXA11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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