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Western Blot (WB) (Western blot analysis of Annexin VIII expression in Jurkat cell lysate.)

Rabbit Annexin VIII Polyclonal Antibody | anti-ANXA8 antibody

Annexin VIII antibody

Gene Names
ANXA8; ANX8; CH17-360D5.2
Applications
Western Blot
Purity
Annexin VIII antibody was purified by affinity chromatography
Synonyms
Annexin VIII; Polyclonal Antibody; Annexin VIII antibody; Polyclonal Annexin VIII; anti-Annexin VIII; SNX; ANXA7; ANX7; Annexin A7; anti-ANXA8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Annexin VIII antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
265
Applicable Applications for anti-ANXA8 antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia cells which may relate its role in hematopoietic cell differentiation.
Cross-Reactivity
Human
Immunogen
Annexin VIII antibody was raised in Rabbit using synthetic peptide surrounding amino acid 316 of human Annexin VIII as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Annexin VIII expression in Jurkat cell lysate.)

Western Blot (WB) (Western blot analysis of Annexin VIII expression in Jurkat cell lysate.)
Related Product Information for anti-ANXA8 antibody
Rabbit polyclonal Annexin VIII antibody
Product Categories/Family for anti-ANXA8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,070 Da
NCBI Official Full Name
annexin A8 isoform 3
NCBI Official Synonym Full Names
annexin A8
NCBI Official Symbol
ANXA8
NCBI Official Synonym Symbols
ANX8; CH17-360D5.2
NCBI Protein Information
annexin A8
UniProt Protein Name
Annexin A8
Protein Family
UniProt Gene Name
ANXA8
UniProt Synonym Gene Names
ANX8; VAC-beta
UniProt Entry Name
ANXA8_HUMAN

NCBI Description

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]

Uniprot Description

ANXA8: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Belongs to the annexin family.

Chromosomal Location of Human Ortholog: 10q11.22

Cellular Component: late endosome membrane; plasma membrane; cytosol

Molecular Function: actin filament binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-3,4,5-triphosphate binding; calcium-dependent phospholipid binding; calcium ion binding; phosphatidylinositol-3,4-bisphosphate binding

Biological Process: endosome organization and biogenesis; endosome transport; blood coagulation

Research Articles on ANXA8

Similar Products

Product Notes

The ANXA8 anxa8 (Catalog #AAA835759) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Annexin VIII can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the ANXA8 anxa8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Annexin VIII, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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