Rabbit anti-Mouse Aminopeptidase A Polyclonal Antibody | anti-ENPEP antibody
Anti-Aminopeptidase A Antibody, Rabbit Polyclonal
Gene Names
Enpep; APA; Ly51; Ly-51; Bp-1/6C3; 6030431M22Rik
Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
Aminopeptidase A; Polyclonal Antibody; Anti-Aminopeptidase A Antibody; Rabbit Polyclonal; ENPEP/Aminopeptidase A Antibody; Rabbit PAb; glutamyl aminopeptidase; Anti-6030431M22Rik Antibody; Anti-APA Antibody; Anti-Bp-1/6C3 Antibody; Anti-ENPEP Antibody; Anti-Ly-51 Antibody; Anti-Ly51 Antibody; anti-ENPEP antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse ENPEP/Aminopeptidase A
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-ENPEP antibody
ELISA (EIA)
Application Notes
ELISA: 1:1000-1:2000
Immunogen
Recombinant Mouse ENPEP/Aminopeptidase A Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Mouse ENPEP/Aminopeptidase A (rM ENPEP/Aminopeptidase A). Total IgG was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-ENPEP antibody
ENPEP, also known as aminopeptidase A, is a member of the peptidase M1 family. Members of this family are involved in response to cadmium ion and proteolysis. They located in 6 components and are expressed in 26 plant structures. ENPEP is expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. It also can be detected in a variety of other tissues. ENPEP probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. ENPEP is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
References
Speth RC, et al. (2008) The significance of brain aminopeptidases in the regulation of the actions of angiotensin peptides in the brain. Heart Fail Rev. 13(3):299-309.Rose JE, et al. (2010) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Mol Med. 16(7-8):247-53.Perez I, et al. (2009) Increased APN/CD13 and acid aminopeptidase activities in head and neck squamous cell carcinoma. Head Neck. 31(10):1335-40.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
107,956 Da
NCBI Official Full Name
glutamyl aminopeptidase
NCBI Official Synonym Full Names
glutamyl aminopeptidase
NCBI Official Symbol
Enpep
NCBI Official Synonym Symbols
APA; Ly51; Ly-51; Bp-1/6C3; 6030431M22Rik
NCBI Protein Information
glutamyl aminopeptidase
UniProt Protein Name
Glutamyl aminopeptidase
Protein Family
UniProt Gene Name
Enpep
UniProt Synonym Gene Names
EAP; AP-A
UniProt Entry Name
AMPE_MOUSE
Uniprot Description
ENPEP: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. Belongs to the peptidase M1 family.
Protein type: Protease; EC 3.4.11.7; Membrane protein, integral
Cellular Component: apical part of cell; apical plasma membrane; brush border; cytoplasmic vesicle; external side of plasma membrane; integral to membrane; lysosomal membrane; membrane; plasma membrane; vesicle membrane
Molecular Function: aminopeptidase activity; hydrolase activity; metal ion binding; metallopeptidase activity; peptidase activity; peptide binding; zinc ion binding
Biological Process: angiogenesis; aromatic compound metabolic process; cell migration; cell proliferation; peptide catabolic process; proteolysis; regulation of blood pressure; regulation of systemic arterial blood pressure by renin-angiotensin
Research Articles on ENPEP
Similar Products
Product Notes
The ENPEP enpep (Catalog #AAA8110928) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Aminopeptidase An Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Aminopeptidase A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:1000-1:2000. Researchers should empirically determine the suitability of the ENPEP enpep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aminopeptidase A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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