Rabbit anti-Human AGXT2 Polyclonal Antibody | anti-AGXT2 antibody

AGXT2, CT (AGXT2, AGT2, Alanine-glyoxylate aminotransferase 2, mitochondrial, (R)-3-amino-2-methylpropionate-pyruvate transaminase, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, D-AIBAT)

Cat. Num. AAA6005295

• Gene Names: AGXT2; AGT2; DAIBAT
• Reactivity: Human
• Applications: ELISA, Western Blot, Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: AGXT2; Polyclonal Antibody; CT (AGXT2; AGT2; Alanine-glyoxylate aminotransferase 2; mitochondrial; (R)-3-amino-2-methylpropionate-pyruvate transaminase; Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-AIBAT); Anti -AGXT2; anti-AGXT2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-AGXT2 antibody: ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Western Blot, Flow Cytometry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Flow Cytometry: 1:10-50
• Immunogen: AGXT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443~473 amino acids from the C-terminal region of human AGXT2.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of AGXT2 Antibody (C-term) in Hela cell line lysates (35ug/lane). AGXT2 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(AGXT2 Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-AGXT2 antibody

The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor.

Product Categories/Family for anti-AGXT2 antibody

Antibodies; Abs to Enzymes; Aminotransferase

NCBI and Uniprot Product Information

• NCBI GI #: 13994255
• NCBI GeneID: 64902
• NCBI Accession #: NP_114106.1
• NCBI GenBank Nucleotide #: NM_031900.3
• UniProt Accession #: Q9BYV1; Q53FB4; Q53FY7; Q53G03; Q5W7Q1
• Molecular Weight: 57,156 Da
• NCBI Official Full Name: alanine--glyoxylate aminotransferase 2, mitochondrial
• NCBI Official Synonym Full Names: alanine--glyoxylate aminotransferase 2
• NCBI Official Symbol: AGXT2
• NCBI Official Synonym Symbols: AGT2; DAIBAT
• NCBI Protein Information: alanine--glyoxylate aminotransferase 2, mitochondrial; beta-ALAAT II; beta-alanine-pyruvate aminotransferase; (R)-3-amino-2-methylpropionate--pyruvate transaminase
• UniProt Protein Name: Alanine--glyoxylate aminotransferase 2, mitochondrial
• Protein Family: Alanine--glyoxylate aminotransferase
• UniProt Gene Name: AGXT2
• UniProt Synonym Gene Names: AGT2; AGT 2
• UniProt Entry Name: AGT2_HUMAN

NCBI Description

The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]

Uniprot Description

AGXT2: is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]

Protein type: Transferase; Mitochondrial; Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.40; EC 2.6.1.44

Chromosomal Location of Human Ortholog: 5p13

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: beta-alanine-pyruvate transaminase activity; alanine-glyoxylate transaminase activity; (R)-3-amino-2-methylpropionate-pyruvate transaminase activity; pyridoxal phosphate binding

Biological Process: pyrimidine nucleoside catabolic process; positive regulation of nitric oxide biosynthetic process; pyrimidine base metabolic process; glyoxylate catabolic process; nucleobase, nucleoside and nucleotide metabolic process; glyoxylate metabolic process; glycine biosynthetic process, by transamination of glyoxylate; L-alanine catabolic process, by transamination