SDS-Page
(Recombinant NUAK1 / ARK5 protein gel 10% SDS-PAGE with Coomassie blue staining MW: 76 kDa Purity: >95%)
NUAK1 recombinant protein
Recombinant NUAK1 (ARK5) protein
Gene Names
NUAK1; ARK5
Synonyms
NUAK1; Recombinant NUAK1 (ARK5) protein; SNF1-like kinase 1; OMPHK1; KIAA0537; NUAK1 recombinant protein
Host
Baculovirus
Form/Format
Recombinant NUAK1/ARK5 protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP
Protein Species
Human
Notes
Recombinant NUAK1/ARK5 protein is suitable for use in in enzyme kinetics, inhibitor screening, and selectivity profiling.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant NUAK1 / ARK5 protein gel 10% SDS-PAGE with Coomassie blue staining MW: 76 kDa Purity: >95%)
SDS-Page
(Recombinant NUAK1 / ARK5 protein gel 10% SDS-PAGE with Coomassie blue staining MW: 76 kDa Purity: >95%)
Related Product Information for NUAK1 recombinant protein
Short Description: Recombinant NUAK1/ARK5 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_055655.1) with a C-terminal DYKDDDDK tag. The molecular weight of the protein is 76 kDa. Recombinant NUAK1/ARK5 protein is suitable for use in in enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: NUAK1, also known as ARK5, is the fifth member of the AMPK catalytic subunit family. It is a serine/ threonine-protein kinase that are activated by phosphorylation at its Ser600 by Akt, which has been reported to be a key player in tumor malignancy. The activated NUAK1 involves in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation an tumor progression, such as it acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1,and Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Which also involves in DNA damage response by phosphorylating p53/ TP53 at 'Ser-15' and 'Ser-392', and it is a sensitive indicator of cellular energy status and have been found to promote tumor cell survival during nutrient starvation.
Background: NUAK1, also known as ARK5, is the fifth member of the AMPK catalytic subunit family. It is a serine/ threonine-protein kinase that are activated by phosphorylation at its Ser600 by Akt, which has been reported to be a key player in tumor malignancy. The activated NUAK1 involves in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation an tumor progression, such as it acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1,and Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Which also involves in DNA damage response by phosphorylating p53/ TP53 at 'Ser-15' and 'Ser-392', and it is a sensitive indicator of cellular energy status and have been found to promote tumor cell survival during nutrient starvation.
Product Categories/Family for NUAK1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,824 Da
NCBI Official Full Name
NUAK family SNF1-like kinase 1
NCBI Official Synonym Full Names
NUAK family kinase 1
NCBI Official Symbol
NUAK1
NCBI Official Synonym Symbols
ARK5
NCBI Protein Information
NUAK family SNF1-like kinase 1
Protein Family
Research Articles on NUAK1
1. MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma.
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Product Notes
The NUAK1 (Catalog #AAA389376) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NUAK1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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