Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using AFAP1L2 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit AFAP1L2 Polyclonal Antibody | anti-AFAP1L2 antibody
AFAP1L2 Antibody
Gene Names
AFAP1L2; XB130; KIAA1914; CTB-1144G6.4
Reactivity
Human, Mouse, RatPredicted: Pig, Bovine, Horse, Rabbit, Dog, Chicken
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
AFAP1L2; Polyclonal Antibody; AFAP1L2 Antibody; Actin filament-associated protein 1-like 2; AF1L2_HUMAN; AFAP1-like protein 2; afap1l2; CTB-1144G6.4; KIAA1914; XB130; anti-AFAP1L2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Horse, Rabbit, Dog, Chicken
Predicted: Pig, Bovine, Horse, Rabbit, Dog, Chicken
Clonality
Polyclonal
Isotype
IgG
Specificity
AFAP1L2 Antibody detects endogenous levels of AFAP1L2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
818
Applicable Applications for anti-AFAP1L2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human AFAP1L2.
Tissue Specificity
Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.
Fragment
Fab Fragment
Conjugate
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using AFAP1L2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using AFAP1L2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Mouse thymus tissue, using AFAP1L2 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Mouse thymus tissue, using AFAP1L2 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-AFAP1L2 antibody
Description: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.
Post Translational Modifications: Tyrosine phosphorylated (by SRC).
Subunit Structure: Interacts with SRC. Interacts with LCK when tyrosine phosphorylated.
Post Translational Modifications: Tyrosine phosphorylated (by SRC).
Subunit Structure: Interacts with SRC. Interacts with LCK when tyrosine phosphorylated.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 130 kDa
Predicted: 92 kDa
Predicted: 92 kDa
NCBI Official Full Name
actin filament-associated protein 1-like 2 isoform 1
NCBI Official Synonym Full Names
actin filament associated protein 1 like 2
NCBI Official Symbol
AFAP1L2
NCBI Official Synonym Symbols
XB130; KIAA1914; CTB-1144G6.4
NCBI Protein Information
actin filament-associated protein 1-like 2
UniProt Protein Name
Actin filament-associated protein 1-like 2
Protein Family
UniProt Gene Name
AFAP1L2
UniProt Synonym Gene Names
KIAA1914; XB130; AFAP1-like protein 2
UniProt Entry Name
AF1L2_HUMAN
Uniprot Description
AFAP1L2: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; Activator
Chromosomal Location of Human Ortholog: 10q25.3
Cellular Component: cytoplasm; plasma membrane
Molecular Function: protein tyrosine kinase activator activity; SH2 domain binding; SH3 domain binding
Biological Process: positive regulation of interleukin-8 production; positive regulation of transcription, DNA-dependent; positive regulation of epidermal growth factor receptor signaling pathway; regulation of mitotic cell cycle; regulation of interleukin-6 production; inflammatory response
Research Articles on AFAP1L2
Similar Products
Product Notes
The AFAP1L2 afap1l2 (Catalog #AAA9611564) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AFAP1L2 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Rabbit, Dog, Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's AFAP1L2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the AFAP1L2 afap1l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AFAP1L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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