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Western Blot (WB) (Western Blot: Sample: Recombinant CAP2, Human.)

Rabbit anti-Human Adenylyl Cyclase Associated Protein 2 Polyclonal Antibody | anti-CAP2 antibody

Polyclonal Antibody to Adenylyl Cyclase Associated Protein 2 (CAP2)

Gene Names
CAP1; CAP; CAP1-PEN
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Adenylyl Cyclase Associated Protein 2; Polyclonal Antibody; Polyclonal Antibody to Adenylyl Cyclase Associated Protein 2 (CAP2); anti-CAP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against CAP2. It has beenselected for its ability to recognize CAP2 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Applicable Applications for anti-CAP2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Fragment
CAP2 (Met1~Ala477)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant CAP2 (Met1~Ala477) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2068427
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant CAP2, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant CAP2, Human.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Brain Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Brain Tissue.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Cerebrum Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Cerebrum Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,830 Da
NCBI Official Full Name
adenylyl cyclase-associated protein 1 isoform a
NCBI Official Synonym Full Names
cyclase associated actin cytoskeleton regulatory protein 1
NCBI Official Symbol
CAP1
NCBI Official Synonym Symbols
CAP; CAP1-PEN
NCBI Protein Information
adenylyl cyclase-associated protein 1
UniProt Protein Name
Adenylyl cyclase-associated protein 1
UniProt Gene Name
CAP1
UniProt Synonym Gene Names
CAP; CAP 1

NCBI Description

The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016]

Uniprot Description

CAP1: an actin binding protein. Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.

Protein type: Actin-binding; Cytoskeletal

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: cortical actin cytoskeleton; extracellular exosome; extracellular region; focal adhesion; plasma membrane

Molecular Function: actin binding; adenylate cyclase binding

Biological Process: actin polymerization or depolymerization; adenylate cyclase activation; ameboidal cell migration; cell morphogenesis; establishment and/or maintenance of cell polarity; neutrophil degranulation; receptor-mediated endocytosis; signal transduction

Research Articles on CAP2

Similar Products

Product Notes

The CAP2 cap1 (Catalog #AAA2025950) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Adenylyl Cyclase Associated Protein 2 (CAP2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Adenylyl Cyclase Associated Protein 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CAP2 cap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adenylyl Cyclase Associated Protein 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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