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Western Blot (WB)

Rabbit ADCY3 Polyclonal Antibody | anti-ADCY3 antibody

ADCY3 Antibody

Gene Names
ADCY3; AC3; AC-III
Reactivity
Dog, Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
ADCY3; Polyclonal Antibody; ADCY3 Antibody; ATP pyrophosphate-lyase 3; olfactive type antibody; anti-ADCY3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Dog, Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Polyclonal
Concentration
0.68 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
1144
Applicable Applications for anti-ADCY3 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunogen
Synthetic peptide generated against a sequence unique to PAC3 protein. All peptides were amidated before conjugation.
Expression
Brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle
Determinant
Affinity Purified
Molecular Function
Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding
Structure
Belongs to adenylyl cyclase class-4 and guanylyl cyclase family. Contains 2 guanylate cyclase domains.
Subcellular Location
Membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-ADCY3 antibody
Particulate Adenylate cyclase type 3 Antibody Affinity Purified
Mediates odorant detection via modulation of intracellular cAMP concentration
Product Categories/Family for anti-ADCY3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
109
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
82,289 Da
NCBI Official Full Name
adenylate cyclase type 3 isoform 2
NCBI Official Synonym Full Names
adenylate cyclase 3
NCBI Official Symbol
ADCY3
NCBI Official Synonym Symbols
AC3; AC-III
NCBI Protein Information
adenylate cyclase type 3
UniProt Protein Name
Adenylate cyclase type 3
Protein Family
UniProt Gene Name
ADCY3
UniProt Synonym Gene Names
KIAA0511; AC-III; AC3
UniProt Entry Name
ADCY3_HUMAN

NCBI Description

This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Uniprot Description

ADCY3: a membrane-associated enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Involved in odorant detection (possibly) via modulation of intracellular cAMP concentration.

Protein type: EC 4.6.1.1; Nucleotide Metabolism - purine; Lyase; Transporter; Membrane protein, integral; Transporter, aquaporin family; Adenylyl cyclase; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cilium; cytoplasm; Golgi apparatus; integral to membrane; integral to plasma membrane; lipid raft; membrane; nucleus; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding; metal ion binding

Biological Process: acrosome reaction; activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; female meiosis; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; olfactory learning; renal water homeostasis; sensory perception of smell; signal transduction; single fertilization; sperm motility

Research Articles on ADCY3

Similar Products

Product Notes

The ADCY3 adcy3 (Catalog #AAA540440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADCY3 Antibody reacts with Dog, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADCY3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the ADCY3 adcy3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADCY3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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