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Western Blot (WB) (Western blot analysis of extracts of mouse placenta tissue, using DLK1 antibody.)

Rabbit DLK1 Polyclonal Antibody | anti-DLK1 antibody

DLK1 Antibody

Gene Names
Dlk1; FA1; ZOG; pG2; DlkI; Peg9; SCP1; DLK-1; Ly107; pref-1; AW742678
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antigen affinity purification
Synonyms
DLK1; Polyclonal Antibody; DLK1 Antibody; DLK; FA1; PREF1; Pref-1; ZOG; pG2; anti-DLK1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
334
Applicable Applications for anti-DLK1 antibody
Western Blot (WB)
Immunogen
A synthetic peptide of human DLK1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8624 / sc-8623 / sc-25437
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of mouse placenta tissue, using DLK1 antibody.)

Western Blot (WB) (Western blot analysis of extracts of mouse placenta tissue, using DLK1 antibody.)
Related Product Information for anti-DLK1 antibody
DLK1 (delta-like-1), also known as fetal antigen 1 (FA1) and preadipocyte factor 1 (pref-1), is a member of the epidermal growth factor (EGF)-like family of proteins, containing six tandem EGF-like repeats (1, 2). DLK1 is a paternally expressed, imprinted gene that plays an important role in normal development and in the maintenence of homeostasis of adipose tissue mass (3). DLK1 deficient mice display growth retardation, obesity, skeletal malformation, and increased serum lipid metabolites (4). It has been reported that the ectodomain of DLK1 is shredded from the cell surface and inhibits adipocyte differentiation (5-7).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
31,121 Da
NCBI Official Full Name
Dlk1
NCBI Official Synonym Full Names
delta-like 1 homolog (Drosophila)
NCBI Official Symbol
Dlk1
NCBI Official Synonym Symbols
FA1; ZOG; pG2; DlkI; Peg9; SCP1; DLK-1; Ly107; pref-1; AW742678
NCBI Protein Information
protein delta homolog 1; adipocyte differentiation inhibitor protein; fetal antigen 1; preadipocyte factor 1; stromal cell derived protein 1
UniProt Protein Name
Protein delta homolog 1
Protein Family
UniProt Gene Name
Dlk1
UniProt Synonym Gene Names
Dlk; Pref1; Scp-1; DLK-1; Pref-1; FA1
UniProt Entry Name
DLK1_MOUSE

Uniprot Description

DLK1: May have a role in neuroendocrine differentiation. Monomer. Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane; external side of plasma membrane

Molecular Function: calcium ion binding

Biological Process: embryonic development; regulation of gene expression; embryonic skeletal development; negative regulation of Notch signaling pathway; cell differentiation; post-embryonic development

Research Articles on DLK1

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Product Notes

The DLK1 dlk1 (Catalog #AAA2529379) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DLK1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DLK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DLK1 dlk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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