Rabbit ADCY2 Polyclonal Antibody | anti-ADCY2 antibody
ADCY2 Antibody BIOTIN-Conjugated
Gene Names
Adcy2; AC2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
ADCY2; Polyclonal Antibody; ADCY2 Antibody BIOTIN-Conjugated; 3'; 5' cyclic AMP synthetase; Adenylate cyclase II; AC2; Adenylate cyclase 2 (brain); ATP pyrophosphate lyase 2; FLJ16822; FLJ45092; HBAC2; KIAA1060; MGC133314; Type II adenylate cyclase antibody; anti-ADCY2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
BIOTIN-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
1090
Applicable Applications for anti-ADCY2 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:1,000
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:1,000
Immunogen
Synthetic peptide corresponding to unique amino acid sequence from rat Particulate Adenylyl Cyclase 2 protein.
Expression
Brain and in lower levels, the olfactory epithelium and lung.
Molecular Function
Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding
Structure
Interacts with RAF1
Subcellular Location
Membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-ADCY2 antibody
BIOTIN-Conjugated Particulate Adenylate cyclase type 2 Antibody
Membrane-bound calmodulin-insensitive adenylyl cyclase.
Membrane-bound calmodulin-insensitive adenylyl cyclase.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
123,316 Da
NCBI Official Full Name
Adenylate cyclase type 2
NCBI Official Synonym Full Names
adenylate cyclase 2 (brain)
NCBI Official Symbol
Adcy2
NCBI Official Synonym Symbols
AC2
NCBI Protein Information
adenylate cyclase type 2
UniProt Protein Name
Adenylate cyclase type 2
Protein Family
UniProt Gene Name
Adcy2
UniProt Synonym Gene Names
AC2
UniProt Entry Name
ADCY2_RAT
NCBI Description
enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate [RGD, Feb 2006]
Uniprot Description
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:22906005, PubMed:24363043, PubMed:10427002, PubMed:1719547, PubMed:7761832, PubMed:21596131, PubMed:11087399, PubMed:15591060, PubMed:19243146, PubMed:16766715). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production (PubMed:24363043). Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (PubMed:22906005).
Research Articles on ADCY2
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Product Notes
The ADCY2 adcy2 (Catalog #AAA542312) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADCY2 Antibody BIOTIN-Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADCY2 can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Confocal Microscopy||1:200 Dot Blot: 1:10,000 ELISA: 1:10,000 Immunocytochemistry: 1:200 Immunofluorescence: 1:200 Immunohistochemistry: 1:200 Immunoprecipitation: 1:200 Western Blot: 1:1,000. Researchers should empirically determine the suitability of the ADCY2 adcy2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADCY2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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