Chicken Protein NLRC5 ELISA Kit | NLRC5 elisa kit

Chicken Protein NLRC5 (NLRC5) ELISA Kit

Cat. Num. AAA2606718

• Gene Names: NLRC5; NOD4; NOD27; CLR16.1
• Reactivity: Chicken
• Synonyms: Protein NLRC5; Chicken Protein NLRC5 (NLRC5) ELISA Kit; NLRC5 elisa kit

• Reactivity: Chicken
• Specificity: No cross-reaction with other factors.
• Sequence Length: 1866

• Samples: Serum, plasma or cell culture supernatant
• Assay Type: Quantitative Sandwich
• Detection Range: 10 ng/ml-0.156 ng/ml
• Sensitivity: Up to 0.05 ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Standard Curve/Testing Data

Related Product Information for NLRC5 elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Chicken NLRC5 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 350529351
• NCBI GeneID: 84166
• NCBI Accession #: NP_115582.4
• NCBI GenBank Nucleotide #: NM_032206.4
• Molecular Weight: 170,417 Da
• NCBI Official Full Name: protein NLRC5
• NCBI Official Synonym Full Names: NLR family, CARD domain containing 5
• NCBI Official Symbol: NLRC5
• NCBI Official Synonym Symbols: NOD4; NOD27; CLR16.1
• NCBI Protein Information: protein NLRC5
• UniProt Protein Name: Protein NLRC5
• Protein Family: Protein
• UniProt Gene Name: NLRC5
• UniProt Synonym Gene Names: NOD27; NOD4; CLR16.1
• UniProt Entry Name: NLRC5_HUMAN

NCBI Description

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]

Uniprot Description

NLRC5: Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. Belongs to the NLRP family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: ATP binding; protein binding

Biological Process: defense response to virus; inhibition of NF-kappaB transcription factor; innate immune response; negative regulation of interferon type I production; positive regulation of MHC class I biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; regulation of kinase activity