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Western Blot (WB) (Western blot analysis of ADAMTSL5 in human skeletal muscle tissue lysate with ADAMTSL5 antibody at 1 ug/mL.)

Rabbit ADAMTSL5 Polyclonal Antibody | anti-ADAMTSL5 antibody

ADAMTSL5 Antibody

Gene Names
ADAMTSL5; THSD6
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
ADAMTSL5; Polyclonal Antibody; ADAMTSL5 Antibody; ADAMTS-like 5; thrombospondin type I domain containing 6; THSD6; anti-ADAMTSL5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
471
Applicable Applications for anti-ADAMTSL5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the carboxy terminus of human ADAMTSL5.
Target Name
ADAMTSL5
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of ADAMTSL5 in human skeletal muscle tissue lysate with ADAMTSL5 antibody at 1 ug/mL.)

Western Blot (WB) (Western blot analysis of ADAMTSL5 in human skeletal muscle tissue lysate with ADAMTSL5 antibody at 1 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 5 ug/mL.)
Related Product Information for anti-ADAMTSL5 antibody
ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
Product Categories/Family for anti-ADAMTSL5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,171 Da
NCBI Official Full Name
ADAMTS-like protein 5
NCBI Official Synonym Full Names
ADAMTS-like 5
NCBI Official Symbol
ADAMTSL5
NCBI Official Synonym Symbols
THSD6
NCBI Protein Information
ADAMTS-like protein 5
UniProt Protein Name
ADAMTS-like protein 5
Protein Family
UniProt Gene Name
ADAMTSL5
UniProt Synonym Gene Names
THSD6; ADAMTSL-5
UniProt Entry Name
ATL5_HUMAN

Uniprot Description

ADAMTSL5: May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM). Interacts with heparin, FBN1 and FBN2. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Secreted; Extracellular matrix; Protease; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: proteinaceous extracellular matrix; extracellular region; microfibril

Molecular Function: heparin binding; zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis

Research Articles on ADAMTSL5

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Product Notes

The ADAMTSL5 adamtsl5 (Catalog #AAA9413489) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAMTSL5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADAMTSL5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ADAMTSL5 adamtsl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAMTSL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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