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Western Blot (WB) (Western blot analysis of KLHL15 in HeLa cell lysate with KLHL15 antibody at (A) 1 and (B) 2 ug/mL.)

Rabbit KLHL15 Polyclonal Antibody | anti-KLHL15 antibody

KLHL15 Antibody

Gene Names
KLHL15; HEL-S-305
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunocytochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
KLHL15; Polyclonal Antibody; KLHL15 Antibody; Kelch-like 15 protein; anti-KLHL15 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
604
Applicable Applications for anti-KLHL15 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide near the carboxy terminus of human KLHL15.
Target Name
KLHL15
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of KLHL15 in HeLa cell lysate with KLHL15 antibody at (A) 1 and (B) 2 ug/mL.)

Western Blot (WB) (Western blot analysis of KLHL15 in HeLa cell lysate with KLHL15 antibody at (A) 1 and (B) 2 ug/mL.)

Immunocytochemistry (ICC)

(Immunocytochemistry of KLHL15 in HeLa cells with KLHL15 antibody at 5 ug/mL.)

Immunocytochemistry (ICC) (Immunocytochemistry of KLHL15 in HeLa cells with KLHL15 antibody at 5 ug/mL.)
Related Product Information for anti-KLHL15 antibody
KLHL15 is a member of a growing superfamily of kelch repeat-containing proteins. The kelch motif was discovered in the sequence of the Drosophila kelch ORF1 protein and forms a conserved beta-propeller tertiary structure. These kelch-like proteins have been implicated in embryogenesis and carcinogenesis through cytoskeleton organization. KLHL15 mRNA is widely expressed in many tissues and is thought to be involved in protein ubiquination and cytoskeleton organization.
Product Categories/Family for anti-KLHL15 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,775 Da
NCBI Official Full Name
kelch-like protein 15
NCBI Official Synonym Full Names
kelch-like family member 15
NCBI Official Symbol
KLHL15
NCBI Official Synonym Symbols
HEL-S-305
NCBI Protein Information
kelch-like protein 15
UniProt Protein Name
Kelch-like protein 15
Protein Family
UniProt Gene Name
KLHL15
UniProt Synonym Gene Names
KIAA1677
UniProt Entry Name
KLH15_HUMAN

NCBI Description

This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009]

Uniprot Description

KLHL15: a substrate-specific adapter for the recruitment of substrates to Cul3-based E3 ubiquitin ligases. KLHL15-Cul3 specifically targets the PP2A regulatory subunit PPP2R5B to promote its turnover by ubiquitylation and proteasomal degradation. May contribute to the selective expression of the PP2A/B holoenzyme in the brain.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: Xp22.1-p21

Biological Process: protein ubiquitination

Research Articles on KLHL15

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Product Notes

The KLHL15 klhl15 (Catalog #AAA9406320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLHL15 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KLHL15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the KLHL15 klhl15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLHL15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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