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Western Blot (WB) (Western blot analysis of 1) Mouse Brain, 2) Rat Brain, with 14-3-3 epsilon Rabbit pAb E12-331 diluted at 1:2, 000.)

Rabbit anti-Rat, Mouse 14-3-3 epsilon Polyclonal Antibody | anti-14-3-3 epsilon antibody

14-3-3 epsilon Rabbit Polyclonal Antibody

Gene Names
YWHAE; MDS; HEL2; MDCR; KCIP-1; 14-3-3E
Reactivity
Rat, Mouse
Applications
Western Blot
Synonyms
14-3-3 epsilon; Polyclonal Antibody; 14-3-3 epsilon Rabbit Polyclonal Antibody; 14-3-3 E; FLJ45465; MDCR; YWHAE; protein kinase C inhibitor protein 1; MDS; KCIP 1; anti-14-3-3 epsilon antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Antibody can detects endogenous 14-3-3 epsilon protein.
Form/Format
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Sequence Length
255
Applicable Applications for anti-14-3-3 epsilon antibody
Western Blot (WB)
Application Notes
WB: 1:1,000
Preparation and Storage
Store at-20 degree C for 1 year. Do not aliquot the antibody.

Western Blot (WB)

(Western blot analysis of 1) Mouse Brain, 2) Rat Brain, with 14-3-3 epsilon Rabbit pAb E12-331 diluted at 1:2, 000.)

Western Blot (WB) (Western blot analysis of 1) Mouse Brain, 2) Rat Brain, with 14-3-3 epsilon Rabbit pAb E12-331 diluted at 1:2, 000.)
Related Product Information for anti-14-3-3 epsilon antibody
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 protein epsilon is a protein that in humans is encoded by the YWHAE gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28KD
NCBI Official Full Name
14-3-3 protein epsilon
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
NCBI Official Symbol
YWHAE
NCBI Official Synonym Symbols
MDS; HEL2; MDCR; KCIP-1; 14-3-3E
NCBI Protein Information
14-3-3 protein epsilon
UniProt Protein Name
14-3-3 protein epsilon
UniProt Gene Name
YWHAE
UniProt Synonym Gene Names
14-3-3E

NCBI Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

Uniprot Description

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm (PubMed:12917326).

Research Articles on 14-3-3 epsilon

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Product Notes

The 14-3-3 epsilon ywhae (Catalog #AAA8502013) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The 14-3-3 epsilon Rabbit Polyclonal Antibody reacts with Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's 14-3-3 epsilon can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1,000. Researchers should empirically determine the suitability of the 14-3-3 epsilon ywhae for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "14-3-3 epsilon, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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