Western Blot (WB)
(Western blot analysis of extracts from COLO cells, using SLC4A8/10 antibody.)
Rabbit anti-Human SLC4A8/10 Polyclonal Antibody | anti-SLC4A8/10 antibody
SLC4A8/10 Antibody
Western Blot (WB)
(Western blot analysis of extracts from COLO cells, using SLC4A8/10 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from COLO cells, using SLC4A8/10 antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]
Uniprot Description
SLC4A10: Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role in regulating intracellular pH. Belongs to the anion exchanger (TC 2.A.31) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q24.2
Cellular Component: integral to plasma membrane; basolateral plasma membrane; integral to membrane; plasma membrane
Molecular Function: inorganic anion exchanger activity; sodium:bicarbonate symporter activity
Biological Process: nervous system development; bicarbonate transport; regulation of intracellular pH; ion transport; chloride transport; transmembrane transport
Research Articles on SLC4A8/10
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Product Notes
The SLC4A8/10 slc4a10 (Catalog #AAA9409590) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC4A8/10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC4A8/10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the SLC4A8/10 slc4a10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC4A8/10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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